Comparision on the sensitivity of MAC- Elisa and pen tax kits in Japanese encephalitis diagnosis

ABSTRACT

Background: \r\n', u'Japanese encephalitis virus (JE) is the most prevalent in Asia, Pacific and in mainland northern Australia; and considered to be the leading cause to the acute encephalitis. The case- fatality and sequela rates in children stay rather high. There were some medical technologies for the JE diagnosis, of which is the application of the expensive MAC- ELISA and PEN TAX kits.\r\n', u'Objectives: \r\n', u'To evaluate and compare the light sensitivity of MAC- ELISA and PENTAX Kits in JE diagnosis.\r\n', u'Subjects and method: \r\n', u'48 pairs of sera samples obtained from the patients with clinically manifested Japanese encephalitis (JE) in 2003- 2005, in some northern provinces, they were applied and tested into MAC- ELISA Kits.\r\n', u'Results:\r\n', u'The sensitivity of MAC- ELISA and PENTAX kits detecting IgM against JE virus were 95.71%, and 98.57%, respectively. In addition to that, the sensitivity of these two kits used to detect JE IgM within the first 7 days of the disease was very high (around 92.31%-96.15%).\r\n', u'Conclusion: \r\n', u'The sensitivity of MAC- ELISA and PENTAX kits used to detect IgM against JE virus was very high. \r\n', u'