Difference of BNP in non-ST-segment elevation myocardial infarction and unstable angina in early differen-tial diagnosis and prognosis of risk assessment / 实用医学杂志

ABSTRACT

Objective To evaluate the difference of B-type natriuretic peptide(BNP)levels between patients with Non-ST elevation myocardial infraction(NSTEMI)and those with unstable angina(UA)and to ex-plore its relationship with the risk factors of major adverse cardiovascular events(MACE)and its value in progno-sis. Methods BNP levels of 110 consecutive patients with NSTE-ACS including 60 cases of NSTEMI and 50 of UA were studied and the incidence of MACE within 6 months after discharge was followed. Results(1)BNP lev-els were higher in NSTEMI group than those in UA group.(2)There were 32 patients suffering from MACE during the following-up.BNP levels were significantly higher in patients with MACE.(3)The risk of suffering from MACE was greater in NSTEMI patients than that in UA patients. Conclusions The level of blood BNP can be used in the differential diagnosis between UA and NSTEMI.Meanwhile,it correlates with the clinical severity and outcome of NSTEMI and may potentially be used as a prognostic marker for NSTEMI.