Extraction Process Optimization of Total Flavonoids in Gynostemma Pentaphyllum by Response Surface A-nalysis / 中国药师
China Pharmacist
; (12): 714-717, 2015.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-669783
Biblioteca responsável:
WPRO
ABSTRACT
Objective:
To optimize the extraction process of total flavonoids in Gynostemma pentaphyllum by the method of response surface analysis ( RSM) .Methods:
Based on the choice of factors and levels according to the results of single factor test, Box-Be-hnken response surface experiment was designed with the extraction rate of total flavonoids as the index to obtaln the best operation con-ditions and two equations of the response surface model.Results:
The optimal extraction conditions of total flavonoids in Gynostemma pentaphyllum were as followsthe volume fraction of ethanol was 71%, the ratio of solid to liquid was 1∶14, and the ultrasonic time was 32 min. Under the conditions, the model predictive value of extraction rate of total flavonoids in Gynostemma pentaphyllum was 4. 676%, and the extraction rate in the verification test was 4. 641%.Conclusion:
The fit of the regression model is good, and the ex-traction technology is feasible and reliable.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo prognóstico
Idioma:
Chinês
Revista:
China Pharmacist
Ano de publicação:
2015
Tipo de documento:
Artigo