Transforming growth factor type beta(TGF—?1 )can increase IL—2R expression and suppress the proliferation of immature(CD~(4-)CD~(8-))thymocytes / 中国免疫学杂志
Chinese Journal of Immunology
; (12)1985.
Article
em Zh
| WPRIM
| ID: wpr-674627
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WPRO
ABSTRACT
Transforming growth factor type ?1(TGF—?1)belong to a family of polypeptides with regulato-ry effects on growth and differention of a variety of cells types.TGF—?1 play an important rolein regulation of immune response by acting as a negative modulate the cell proliferation throughstill unknow mechanisms.We investigated the effect of TGF—?1 on the IL—2R expression andproliferation activited DN cells and we observed that TGF—?1 was able to increase the expres-sion of IL—2R in DN cells and to suppress the proliferation of DN cells and we have discussedabout these results.
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Base de dados:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Immunology
Ano de publicação:
1985
Tipo de documento:
Article