Inhibited effects of progesterone on contraction and cytomembrane Ca~(2+)-activated K~(+)currents in guinea pig colonic smooth muscles / 中国药理学通报
Chinese Pharmacological Bulletin
; (12)2003.
Article
em Zh
| WPRIM
| ID: wpr-678521
Biblioteca responsável:
WPRO
ABSTRACT
AIM To study the effects of progesterone on contractile activity of smooth muscle stripes and the large conduction Ca 2+ activated K + currents (BK Ca ) of single colonic myocytes in female guinea pig proximal colons METHODS Stripes and single cells were separated acutely from guinea pig proximal colon Contractions of stripes were measured by isonic transducer, and Ca 2+ activated K + currents were recorded with an Axopatch 1D amplifier under conventional whole cell patterns RESULTS 64 8 ?mol?L -1 progesterone produced longitudinal stripes significantly re laxation(0 1792 g?0 0873 g, n =6, P
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Base de dados:
WPRIM
Idioma:
Zh
Revista:
Chinese Pharmacological Bulletin
Ano de publicação:
2003
Tipo de documento:
Article