Pathogenic Mechanisms of the Focal Segmental Glomerulosclerosis and Its Role in the Progression of IgA Nephropathy / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
; (6): 549-555, 2018.
Article
em Zh
| WPRIM
| ID: wpr-690297
Biblioteca responsável:
WPRO
ABSTRACT
Focal segmental glomerulosclerosis (FSGS),a common pathological change in kidney diseases,may be caused by primary factors or multiple secondary factors. Its pathogenic mechanism remains a hot topic in kidney disease research. FSGS-like pathologic changes are highly in IgA nephropathy. It has been speculated that FSGS in IgA nephropathy might be caused by hemodynamics changes,and podocyte injury,which,however,have not been well documented. Our current review focuses on the pathogenesis of secondary FSGS and its role in the progression of IgA nephropathy,with an attempt to provide more insights in the treatment of IgA nephropathy.
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WPRIM
Idioma:
Zh
Revista:
Acta Academiae Medicinae Sinicae
Ano de publicação:
2018
Tipo de documento:
Article