Effect of laparoscopic hysterectomy on vaginal microflora and the effect of lactobacillus intervention / 国际检验医学杂志

ABSTRACT

Objective To analyze the effect of laparoscopic hysterectomy on vaginal microflora and the effect of lactobacillus intervention.Methods 80 female patients undergoing laparoscopic hysterectomy in Wu-han University of Science and Technology Hospital from May 2014 to December 2016 were enrolled in the study.The patients were randomly divided into the observation group and the control group,40 cases in each group.The observation group received 3 courses of intervention with Live Lactobacillus Capule for Vsginal Use in 3 months after operation while the control group were not given any treatment.The rate of vaginal mi-croecological imbalance,the detection rate of lactobacillus,pH and female sexual function index(FSFI)were compared between the two groups.Results 2 month and 3 month after operation,there were significant differ-ences in the density of vaginal microflora,the diversity of vaginal microflora,the vaginal pH and the number of vaginal lactobacilli,compared with those before operation(P<0.05).3 month after operation,the above inde-xes were significantly better than those at 2 month after operation(P<0.05).After treatment,the rate of va-ginal microecological imbalance and vaginal pH value were lower in the observation group than the control group[37.50% vs.70.00%,(4.81 ± 0.26)vs.(5.16 ± 1.02)],while the detection rate of vaginal lactobacil-lus and FSFI score were higher than the control group[97.50% vs.57.50%,(81.14 ± 1.75)vs.(75.34 ± 1.18)](P<0.05).Conclusion Laparoscopic hysterectomy may affect vaginal microflora in the female,espe-cially 2 month after operation,the microecological environment is relatively poor.The application of Live Lac-tobacillus Capule for Vsginal Use can improve the vaginal microecological environment and the quality of sex-ual life,which is worth of clinical promotion.