Ceftriaxone-Induced Acute Pancreatitis in Patient with Liver Abscess / 대한췌담도학회지
Korean Journal of Pancreas and Biliary Tract
; : 82-86, 2018.
Article
em En
| WPRIM
| ID: wpr-714144
Biblioteca responsável:
WPRO
ABSTRACT
Acute pancreatitis is a rare complication in patients treated with ceftriaxone. Precipitation of ceftriaxone in the bile causes the formation of biliary sludge leading to the development of cholangitis, cholecystitis, or pancreatitis. We treated a patient with acute pancreatitis who developed this condition after the administration of ceftriaxone. A 70-year-old man presented in a drowsy state with fever. He was diagnosed with a liver abscess and treated with intravenously administrated ceftriaxone and metronidazole. He complained of dyspepsia and epigastric pain on the 25th day of ceftriaxone administration. Laboratory examination and abdominal computed tomography revealed biliary pancreatitis. Ceftriaxone-induced acute pancreatitis was suspected, and ceftriaxone administration was immediately discontinued. Two days later, serum amylase and lipase levels recovered to within reference range, and he showed rapid resolution of symptoms. We concluded that ceftriaxone results in the formation of biliary sludge and causes serious adverse events such as cholecystitis, cholangitis and biliary pancreatitis.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Pancreatite
/
Valores de Referência
/
Bile
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Ceftriaxona
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Colangite
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Colecistite
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Dispepsia
/
Febre
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Amilases
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Lipase
Limite:
Aged
/
Humans
Idioma:
En
Revista:
Korean Journal of Pancreas and Biliary Tract
Ano de publicação:
2018
Tipo de documento:
Article