Neutrophil-to-lymphocyte Ratio as A Predictor of Aspiration Pneumonia in Drug Intoxication Patients
Journal of The Korean Society of Clinical Toxicology
; : 61-67, 2018.
Article
em En
| WPRIM
| ID: wpr-719084
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE: To evaluate the association between neutrophil-to-lymphocyte ratio (NLR) and occurrence of aspiration pneumonia in drug intoxication (DI) patients in the emergency department (ED) and to evaluate the relationship between NLR and length of hospital admission/intensive care unit (ICU) admission. METHODS: A total of 466 patients diagnosed with DI in the ED from January 2016 to December 2017 were included in the analysis. The clinical and laboratory results, including NLR, were evaluated as variables. NLR was calculated as the absolute neutrophil count/absolute lymphocyte count. To evaluate the prognosis of DI, data on the development of aspiration pneumonia were obtained. Also, we evaluated the relationship between NLR and length of hospital admission and between NLR and length of ICU admission. Statistically, multivariate logistic regression analyses, receiver-operating characteristic (ROC) curve analysis, and Pearson's correlation (ρ) were performed. RESULTS: Among the 466 DI patients, 86 (18.5%) developed aspiration pneumonia. Multivariate logistic regression analysis revealed NLR as an independent factor in predicting aspiration pneumonia (odds ratio, 1.7; p=0.001). NLR showed excellent predictive performance for aspiration pneumonia (areas under the ROC curves, 0.815; cut-off value, 3.47; p 3.47).
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Pneumonia Aspirativa
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Prognóstico
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Modelos Logísticos
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Curva ROC
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Sensibilidade e Especificidade
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Contagem de Linfócitos
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Emergências
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Medicina de Emergência
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Serviço Hospitalar de Emergência
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Neutrófilos
Tipo de estudo:
Diagnostic_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Humans
Idioma:
En
Revista:
Journal of The Korean Society of Clinical Toxicology
Ano de publicação:
2018
Tipo de documento:
Article