Indoor pet ownership in infancy is a risk factor for the development of sensitization to pets and asthma in childhood
Allergy, Asthma & Respiratory Disease
; : 99-105, 2019.
Article
em Ko
| WPRIM
| ID: wpr-739512
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE: It is controversial whether indoor pet exposure is either a risk or protective factor developing sensitization to pet allergens or asthma. Therefore, we investigated whether indoor pet ownership entails a risk for the development of asthma and sensitization in childhood. METHODS: The Panel Study of Korean Children (PSKC) is a general-population-based birth cohort study that recruited 2,078 mother-baby dyads in Korea between April and July of 2008. Among 1,577 children who were followed up in 2015, 559 underwent skin prick tests, spirometry and bronchial provocation tests using Provocholine. Having a cat or a dog and the prevalence of asthma were evaluated by using self-reported questionnaires and physicians’ medical records. RESULTS: During infancy, the rate of dog ownership was 4.5% (71 of 1,574) and that of cat ownership was 0.5% (8 of 1,574). Of the subjects, 7.9% (n=109) currently had at least 1 dog and 2.5% (n=34) had at least 1 cat. Pet ownership during infancy was associated with sensitization to cats or dogs (adjusted odds ratio [aOR], 4.24; 95% confidence interval [CI], 1.29–13.98), wheezing within 12 months (aOR, 5.56; 95% CI, 1.65–18.75) and current asthma (wheezing episode in the last 12 months+diagnosed asthma by physicians) (aOR, 6.36; 95% CI, 1.54–26.28). In contrast, pet ownership during the last 12 months was not associated with sensitization to cats or dogs or current asthma. CONCLUSION: Indoor pet exposure during infancy can be critical for developing sensitization to cats or dogs and asthma in childhood. Avoidance of pet exposure in early life may reduce sensitization to cats or dogs and development of asthma.
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Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Propriedade
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Asma
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Pele
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Espirometria
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Testes de Provocação Brônquica
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Alérgenos
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Razão de Chances
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Sons Respiratórios
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Prontuários Médicos
/
Prevalência
Tipo de estudo:
Etiology_studies
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Incidence_studies
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Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limite:
Animals
/
Humans
País/Região como assunto:
Asia
Idioma:
Ko
Revista:
Allergy, Asthma & Respiratory Disease
Ano de publicação:
2019
Tipo de documento:
Article