A Case of Cerebral Toxoplasmosis Following Tandem Autologous Stem Cell Transplantation in a Multiple Myeloma Patient / 감염과화학요법
Infection and Chemotherapy
; : 181-186, 2010.
Article
em En
| WPRIM
| ID: wpr-75401
Biblioteca responsável:
WPRO
ABSTRACT
Toxoplasmosis is a rare but fatal complication in hematopoietic stem cell transplant recipients, usually associated with allogeneic hematopoietic stem cell transplantation (HSCT). We report a case of cerebral toxoplasmosis in a patient with multiple myeloma, following tandem autologous stem cell transplantation. A 55-year-old Korean male presented with weakness in both legs that had progressed to both arms. A magnetic resonance imaging scan of the brain revealed multiple, variable-sized ring-enhancing lesions with surrounding edema in the cerebral hemispheres and brain stem. Stereotactic biopsy revealed bradyzoites of Toxoplasma gondii in the brain tissue. The patient received trimethoprim-sulfamethoxazole, followed by pyrimethamine and sulfadiazine, accompanying treatment for progressive multiple myeloma. Cerebral toxoplasmosis should be considered as one of the differential diagnoses in patients with neurologic signs following autologous HSCT.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Braço
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Pirimetamina
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Células-Tronco
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Sulfadiazina
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Toxoplasma
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Biópsia
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Encéfalo
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Tronco Encefálico
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Células-Tronco Hematopoéticas
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Imageamento por Ressonância Magnética
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
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Male
Idioma:
En
Revista:
Infection and Chemotherapy
Ano de publicação:
2010
Tipo de documento:
Article