Trends of CD4+T lymphocyte counts in acquired immune deficiency syndrome patients in Tianjin from 2005 to 2017 / 中华传染病杂志
Chinese Journal of Infectious Diseases
; (12): 403-407, 2019.
Article
em Zh
| WPRIM
| ID: wpr-754669
Biblioteca responsável:
WPRO
ABSTRACT
Objective To assess the trends and characteristics of CD 4 +T lymphocyte counts among patients with acquired immune deficiency syndrome ( AIDS) in Tianjin City.Methods The demographic and clinical characteristics of AIDS patients diagnosed in Tianjin Second People′s Hospital from 2005 to 2017 were analyzed.The CD4 +T lymphocyte count and the frequency of CD 4+T lymphocyte count <200 cells/μL were analyzed according to age , transmission route and education level.The chi-square test was used for counting data.The rank sum test was used for the data that did not conform to normal distribution .Results The 3 062 patients were aged (38.2 ±11.9) years.There were 2 867 males (93.6%) aged (37.8 ±11.8) years, and 195 female patients ( 6.4%) aged (43.3 ±12.6) years.The CD4+T lymphocyte counts of these patients presented an increasing trend from 2005 to 2017, with statistically significant differences among different years (Z=18.871, P<0.05).The frequency of CD4 +T lymphocytes <200 cells/μL showed a decreasing trend , with statistically significant difference in different years (χ2 =7.017,P<0.05).The CD4+T lymphocyte counts in patients of all age groups showed an increasing trend from 2005 to 2017, with statistically significant differences (Z=6.849, 9.532, 7.146, 6.874, 8.038, 11.249, and 10.059, respectively, all P<0.05).The CD4+T lymphocyte counts in homosexual patients presented an increasing trend , with statistical significance in different years (Z=8.038, P<0.05).The CD4+T lymphocyte counts in patients who received education more than 13 years (include 13 years) presented an increasing trend , with statistical significance (Z=4.573, P< 0.05).Conclusions The median CD4+T lymphocyte counts of AIDS patients receiving primary treatment in Tianjin city are increasing by years , while the proportion of severe immunosuppression is decreasing.Patients who are infected through homosexual transmission and those with high level of education seek medical care earlier.
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Base de dados:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Infectious Diseases
Ano de publicação:
2019
Tipo de documento:
Article