Frozen Cytology of Meningeal Malignant Solitary Fibrous Tumor/Hemangiopericytoma
Journal of Pathology and Translational Medicine
; : 192-197, 2019.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-766016
Biblioteca responsável:
WPRO
ABSTRACT
A 51-year-old woman presented with severe dizziness. The brain magnetic resonance image revealed a 5.5 cm multiloculated mass with a thick rim in the left temporal lobe. Cytological examination of frozen diagnosis of the mass showed hypercellular sheets of round and rhabdoid cells in a hemorrhagic background, and two mitotic figures were observed. Histologically, the excised dura-based mass consisted of predominantly round cells with small foci of rhabdoid tumor cells in a pseudoalveolar pattern in a hemorrhagic background, and the cells showed nuclear positivity for signal transducer and activator of transcription 6 as well as frequent mitosis. The mass was diagnosed as a grade 3 solitary fibrous tumor (SFT)/hemangiopericytoma (HPC). The cytological diagnosis of SFT/HPC is challenging because of the heterogeneous cytological findings, such as histological heterogeneity, and because there are no standardized cytological criteria for malignant SFT/HPC. Cytological findings, such as singly scattered small cells, hypercellularity, rare ropy collagen, and round and rhabdoid cells with pseudoalveolar pattern, may assist in the diagnosis of malignant SFT/HPC.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Lobo Temporal
/
Características da População
/
Encéfalo
/
Sistema Nervoso Central
/
Colágeno
/
Tumor Rabdoide
/
Diagnóstico
/
Tontura
/
Fator de Transcrição STAT6
/
Tumores Fibrosos Solitários
Tipo de estudo:
Estudo diagnóstico
Aspecto:
Determinantes sociais da saúde
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Journal of Pathology and Translational Medicine
Ano de publicação:
2019
Tipo de documento:
Artigo