Four new corynanthe-type alkaloids from the roots of Alstonia scholaris / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
; (6): 918-923, 2019.
Article
em En
| WPRIM
| ID: wpr-781237
Biblioteca responsável:
WPRO
ABSTRACT
Four new corynanthe-type alkaloids, meloslines C-F (1-4), together with four known ones (5-8) were isolated from the roots of Alstonia scholaris. Their structures including absolute configurations were elucidated by extensive spectroscopic analysis and electronic circular dichroism (ECD) calculation. Compounds 1 and 2 exhibited potent vasorelaxant activity on endothelium-intact renal arteries precontracted with KCl.
Texto completo:
1
Base de dados:
WPRIM
Idioma:
En
Revista:
Chinese Journal of Natural Medicines (English Ed.)
Ano de publicação:
2019
Tipo de documento:
Article