Optical coherence tomography angiography in preclinical neuroimaging
Biomedical Engineering Letters
; (4): 311-325, 2019.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-785521
Biblioteca responsável:
WPRO
ABSTRACT
Preclinical neuroimaging allows for the assessment of brain anatomy, connectivity, and function in laboratory animals, such as mice and this imaging field has been a rapidly growing aimed at bridging the translation gap between animal and human research. The progress in the animal research could be accelerated by high-resolution in vivo optical imaging technologies. Optical coherence tomography-based angiography (OCTA) estimates the scattering from moving red blood cells, providing the visualization of functional micro-vessel networks within tissue beds in vivo without a need for exogenous contrast agents. Recent advancement of OCTA methods have expanded its application to neuroimaging of small animal models of brain disorders. In this paper, we overview the recent development of OCTA techniques for blood flow imaging and its preclinical applications in neuroimaging. In specific, a summary of preclinical OCTA studies for traumatic brain injury, cerebral stroke, and aging brain on mice is reviewed.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Encéfalo
/
Encefalopatias
/
Lesões Encefálicas
/
Envelhecimento
/
Angiografia
/
Meios de Contraste
/
Acidente Vascular Cerebral
/
Modelos Animais
/
Experimentação Animal
/
Tomografia de Coerência Óptica
Limite:
Animais
/
Humanos
Idioma:
Inglês
Revista:
Biomedical Engineering Letters
Ano de publicação:
2019
Tipo de documento:
Artigo