Advances on hypoglycemic activity and mechanism of triterpenoids / 中国药科大学学报
Journal of China Pharmaceutical University
; (6): 764-770, 2015.
Article
em Zh
| WPRIM
| ID: wpr-812005
Biblioteca responsável:
WPRO
ABSTRACT
@#The research of triterpenoids on hypoglycemic and anti-diabetic activities have made great progress. Findings indicated that triterpenoids could reduce blood glucose via different mechanisms, including increasing insulin secretion, enhancing insulin sensitivity, promoting glucose uptake by activation of AMP-activated protein kinase(AMPK), decreasing glycogenolysis and gluconeogenesis, and inhibiting protein tyrosine phosphates 1B(PTP1B), α-glycosidase, aldose reductase(AR)and dipeptidyl peptidase-4(DPP-4). This article reviews the hypoglycemic effects and mechanisms of triterpenoids, providing the reference for further research and development of triterpenoids.
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Base de dados:
WPRIM
Idioma:
Zh
Revista:
Journal of China Pharmaceutical University
Ano de publicação:
2015
Tipo de documento:
Article