Testosterone Undecanoate Pills improves insulin resistance in type-2 diabetes men with hypogonadism / 中华男科学杂志
National Journal of Andrology
; (12): 517-521, 2017.
Article
em Zh
| WPRIM
| ID: wpr-812732
Biblioteca responsável:
WPRO
ABSTRACT
Objective@#To evaluate the effects of Testosterone Undecanoate Pills (TUP) on insulin resistance (IR) in type-2 diabetes men with hypogonadism.@*METHODS@#We randomly divided 82 type-2 diabetes patients with hypogonadism into a treatment (n = 42) and a control group (n = 40), both maintaining their glucose- and lipid-reducing therapies, while the former treated orally with TUP in addition. After 6 months of medication, we compared the body mass index (BMI), waist circumference (WC), blood glucose level, HbA1c, lipid profile, IR index obtained by homeostatic model assessment (HOMA-IR), insulin sensitivity index (ISI), sex hormone levels, and sexual function scores between the two groups of patients.@*RESULTS@#Compared with the baseline, the patients in the treatment group showed significant decreases after medication in BMI ([26.71 ± 2.39] vs [25.15 ± 2.28] kg/m2, P 0.05).@*CONCLUSIONS@#TUP can significantly improve insulin resistance in type-2 diabetes men with hypogonadism.
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Testosterona
/
Sangue
/
Glicemia
/
Hemoglobinas Glicadas
/
Resistência à Insulina
/
Índice de Massa Corporal
/
Usos Terapêuticos
/
Diabetes Mellitus Tipo 2
/
Tratamento Farmacológico
/
Circunferência da Cintura
Tipo de estudo:
Prognostic_studies
Limite:
Humans
/
Male
Idioma:
Zh
Revista:
National Journal of Andrology
Ano de publicação:
2017
Tipo de documento:
Article