Relationship between Angiographic Late Loss and 5-Year Clinical Outcome after Drug-Eluting Stent Implantation
Yonsei Medical Journal
; : 41-47, 2013.
Article
em En
| WPRIM
| ID: wpr-82708
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE:
Currently, insufficient data exist to evaluate the relationship between angiographic late loss (LL) and long-term clinical outcome after drug-eluting stent (DES) implantation. In this study, we hypothesized that angiographic LL between 0.3 and 0.6 mm correlate with favorable long-term clinical outcomes. MATERIALS ANDMETHODS:
Patients were enrolled in the present study if they had undergone both DES implantation in single coronary vessel and a subsequent follow-up angiogram (n=634). These individuals were then subdivided into three groups based on their relative angiographic LL group I (angiographic LL 0.6 mm, n=134). During a 5-year follow-up period, all subjects were tracked for critical events, defined as any cause of death or myocardial infarction, which were then compared among the three groups.RESULTS:
Mean follow-up duration was 63.0+/-10.0 months. Critical events occurred in 25 subjects in group I (6.6%), 5 in group II (4.0%), and 17 in group III (12.7%), (p=0.020; group I vs. group II, p=0.293; group II vs. group III, p=0.013). In a subsequent multivariate logistic regression analysis, chronic renal failure [odds ratio (OR)=3.29, 95% confidence interval (CI) 1.48-7.31, p=0.003] and long lesion length, defined as lesion length >28 mm (OR=1.88, 95% CI 1.02-3.46, p=0.042) were independent predictors of long-term critical events.CONCLUSION:
This retrospective analysis fails to demonstrate that post-DES implantation angiographic LL between 0.3 and 0.6 mm is protective against future critical events.Palavras-chave
Texto completo:
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Base de dados:
WPRIM
Assunto principal:
Fatores de Tempo
/
Doença da Artéria Coronariana
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Falha de Prótese
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Angiografia
/
Razão de Chances
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Análise Multivariada
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Estudos Retrospectivos
/
Seguimentos
/
Resultado do Tratamento
/
Vasos Coronários
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
Limite:
Adult
/
Aged
/
Female
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Humans
/
Male
Idioma:
En
Revista:
Yonsei Medical Journal
Ano de publicação:
2013
Tipo de documento:
Article