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Alkaloid constituents from the fruits of Flueggea virosa / 中国天然药物
Article em En | WPRIM | ID: wpr-827231
Biblioteca responsável: WPRO
ABSTRACT
Three new indole alkaloids, flueindolines A-C (1-3), along with nine known alkaloids (4-12), were isolated from the fruits of Flueggea virosa (Roxb. ex Willd.) Voigt. Compounds 1 and 2 are two new fused tricyclic indole alkaloids possessing an unusual pyrido[1, 2-a]indole framework, and 3 presents a rare spiro (pyrrolizidinyl-oxindole) backbone. Their structures with absolute configurations were elucidated by means of comprehensive spectroscopic analysis, chemical calculation, as well as X-ray crystallography. Chiral resolution and absolute configuration determination of the known compounds 4, 10, and 11 were reported for the first time. The hypothetical biogenetical pathways of 1-3 were herein also proposed.
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Texto completo: 1 Base de dados: WPRIM Idioma: En Revista: Chinese Journal of Natural Medicines (English Ed.) Ano de publicação: 2020 Tipo de documento: Article
Texto completo: 1 Base de dados: WPRIM Idioma: En Revista: Chinese Journal of Natural Medicines (English Ed.) Ano de publicação: 2020 Tipo de documento: Article