Diagnosis and Management of Chronic Kidney Disease-Mineral Bone Disease in Children

ABSTRACT

Chronic kidney disease–mineral bone disorder (CKD–MBD) is a systemic disorderof mineral and bone metabolism caused by CKD. Patients with early-stage CKDwho present with disordered regulation of bone and mineral metabolism may beasymptomatic. However, if untreated, the condition can be a significant barrierin achieving optimal bone strength, linear growth, and cardiovascular health inpediatric patients with CKD. Thus, the current study evaluated the definition, pathogenesis,diagnosis, and management of pediatric CKD-MBD.