Characteristics and functions of exosomes from different cell sources / 国际药学研究杂志

ABSTRACT

Exosomes, cystic vesicles secreted by living cells, carry lipids, proteins and genetic materials, and transmits biological informations in the body. The unique tissue or cell-specific proteins and genetic materials in the exo- somes generally reflect the cell origin and the physiological state of cells, so the exosomes from different cell sources appear to have different characteristics and functions. In view of the endogenous character, biocompatibility and functional versatility, the exosomes are expected to be a new means for the drug delivery systems, immunotherapies, and precision treatment. This review summarizes the exosomes secreted by different cells, focusing on the research achievement in their characteristics and functionalization studies in recent years.