Pulmonary drug delivery systems and progress in their applications to lung disease treatment / 国际药学研究杂志
Journal of International Pharmaceutical Research
; (6): 289-295, 2015.
Article
em Zh
| WPRIM
| ID: wpr-845685
Biblioteca responsável:
WPRO
ABSTRACT
Pulmonary drug delivery systems (PDDS) have some advantages, including high drug accumulation in the lungs, no first pass effect, and rapid absorption of drugs. They have become a key way to treat lung diseases and improve the absorption of biomacromolecules. In this review, we analyze lung's physiological features, and discuss the main dosage forms of lung inhalations, their preparation methods, the evaluation methods, and the in vivo experimental methods. The applications of pulmonary drug delivery to lung diseases, including acute lung injury, pulmonary infection, pulmonary fibrosis, asthma, chronic obstructive pulmonary disease, and lung cancer, are also discussed.
Texto completo:
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Base de dados:
WPRIM
Idioma:
Zh
Revista:
Journal of International Pharmaceutical Research
Ano de publicação:
2015
Tipo de documento:
Article