Chemical constituents of xanthone in Swertia kingii / 中草药

ABSTRACT

Objective: To study the chemical constituents of the roots of Swertia kingii. Methods: The chemical constituents were isolated and purified by silica gel and Sephadex LH-20 chromatographies. Their structures were identified on the basis of physicochemical properties and spectrometric data. Results: Ten compounds obtained from this plant were identified as demethylbellidifolin (1), β-sitosterol (2), 1,3,7-trihydro-xanthone (3), swertianolin (4), 1,3,7-trihydrox-8-methoxy-xanthone (5), 1,5,8- trihydroxy-3-methoxy-xanthone (6), 1,3,7,8-tetrahydroxyxanthone-1-O-β-D-glucopyranoside (7), 1,3,7,8-tetrahydroxy-xanthone (8), 1-hydroxy-3,7,8-trimethoxy-xanthone (9), and 1,2,6,8-tetrahydroxy-xanthone (10). Conclusion: Except for compound 2, the other compounds are obtained from this plant for the first time.