Therapeutic Drug Monitoring and Individualized Medication of Ribavirin / 中国药学杂志
Chinese Pharmaceutical Journal
; (24): 1229-1233, 2020.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-857619
Biblioteca responsável:
WPRO
ABSTRACT
Ribavirin is a widely used nucleoside antiviral drug. During the epidemic of coronavirus disease 2019 (COVID-19), ribavirin was recommended for empirical treatment in the Clinical Management of Human Infection with COVID-19 (trial guidance v6). However, due to the large inter-individual variations in dose-response relationship, and extremely long terminal half time, it is necessary to perform therapeutic drug monitoring and individualized dose adjustment for ribavirin in special populations. In this article, the pharmacokinetics and therapeutic drug monitoring of ribavirin in different populations are reviewed in order to provide reference for clinical rational use and individualized medication of ribavirin for treatment of COVID-19.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Guia de prática clínica
Idioma:
Chinês
Revista:
Chinese Pharmaceutical Journal
Ano de publicação:
2020
Tipo de documento:
Artigo