Advances Research on Mechanism of Traditional Chinese MedicineAgainst Damp-heat Syndrome / 中国实验方剂学杂志

ABSTRACT

By summarizing the existing researches on the prevention and treatment of damp-heat syndrome with traditional Chinese medicine（TCM）， this paper digitized the TCM syndromes of damp-heat syndrome， enriched the TCM theories， and provided reference for the prevention and treatment of damp-heat syndrome and provided innovative ideas for the research of damp-heat syndrome. Damp-heat syndrome can cause pathological changes all over the body. It is easy to induce a variety of acute febrile diseases， including ulcerative colitis， chronic gastritis， chronic hepatitis B， chronic kidney disease， irritable bowel syndrome， pneumonia， cough and asthma， which seriously affects the health of the body. Damp-heat syndrome can be divided into syndrome of damp-heat in upper Jiao， syndrome of damp-heat in middle Jiao and syndrome of damp-heat in lower Jiao .At the same time it can be divided into damp-heat obstructing the lung， large intestine damp-heat， damp-heat containing the spleen， liver-gallbladder damp-heat， and bladder damp-heat syndrome ， nephritic damp-heat syndrome by simulating clinical pathogeny according to basic theories of TCM. Heat-clearing and dampness-expelling is the treatment principle of damp-heat syndrome. TCM achieves the purpose of treating damp-heat syndrome by virtue of its anti-inflammation， anti-oxidation， regulation of intestinal flora， lowering blood glucose， lowering blood lipid and enhancing immunity. Based on the two aspects of TCM and prescription， the application， mainly in the syndrome differentiation of triple energizer differentiation， visceral syndrome differentiation is complementary， pharmacological action and mechanism of TCM in prevention and treatment of damp heat syndrome are reviewed in detail， which is a concrete analysis and discussion， in order to provide relevant experience for data integration and system construction of damp heat syndrome， and provide new ideas and help for follow-up clinical drug research and development and optimization innovation of damp heat syndrome. At present， the material basis and relevant prevention and treatment mechanism of dampness-heat syndrome are still not clear in China， so it is necessary to further study and explore its potential biological diagnostic markers， strengthen the research and development of new Chinese medicine preparation against dampness-heat， and elaborate the mechanism of action of Chinese medicine on damp-heat syndrome in multiple ways and directions.