High-risk endoscopic features and therapeutic efficacy of endoscopic treatment of sporadic non-ampullary descending duodenal adenoma / 中华消化内镜杂志
Chinese Journal of Digestive Endoscopy
; (12): 226-230, 2021.
Article
em Zh
| WPRIM
| ID: wpr-885713
Biblioteca responsável:
WPRO
ABSTRACT
Objective:To investigate the safety and efficacy of endoscopic treatment for sporadic non-ampullary descending duodenal adenoma, and to analyze high-risk endoscopic features of malignant adenoma.Methods:Data of 54 patients diagnosed as having non-ampullary descending duodenal adenoma in Nanjing Drum Tower Hospital from November 2012 to September 2019 were retrospectively studied. The patients were divided into two groups, the high-grade intraepithelial neoplasia/adenocarcinoma (HGIN/AC) group and the low-grade intraepithelial neoplasia (LGIN) group according to pathological grade. Clinical features including gender, age, size and color of lesions, therapeutic methods, complications and postoperative follow-up results were analyzed.Results:A total of 54 patients were divided into the HGIN/AC group ( n=12) and the LGIN group ( n=42). There were significant differences in size or color of lesions between the two groups (both P<0.05). All 54 patients received endoscopic treatment. Biopsy, endoscopic mucosal resection and endoscopic submucosal dissection were performed on 8, 32 and 14 cases, respectively. A small perforation was found and clipped during operation without any complications. There were 2 cases of delayed hemorrhage, and the bleeding stopped under endoscopic treatment. The mean follow-up time was 2-58 months with no recurrence. Conclusion:Endoscopic treatment is safe and effective for non-ampullary descending duodenal adenoma. Lesions of size larger than 10 mm and those with a red surface have higher malignant tendency.
Texto completo:
1
Base de dados:
WPRIM
Tipo de estudo:
Etiology_studies
Idioma:
Zh
Revista:
Chinese Journal of Digestive Endoscopy
Ano de publicação:
2021
Tipo de documento:
Article