Research Progress of Discoidin Domain Receptor 1 in Breast Cancer and Other Malignant Tumors / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
; (6): 634-641, 2021.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-887905
Biblioteca responsável:
WPRO
ABSTRACT
Discoidin domain receptor 1(DDR1)is a critical member of the receptor tyrosine kinase family.It may be related to tumor invasion and metastasis,and the abnormal activation of DDR1 can lead to the occurrence and development of malignant tumors,inflammation,and fibrosis.DDR1 are involved in cell adhesion,migration,proliferation,secretion of cytokines,and remodeling of extracellular matrix,thus playing a critical role in various pathophysiological processes of the human body.In this review,we demonstrate the research progress of DDR1 in breast cancer and other malignant tumors,in order to provide a new theoretical basis for the prevention and treatment of breast cancer and other tumors.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fibrose
/
Neoplasias da Mama
/
Adesão Celular
/
Receptores Proteína Tirosina Quinases
/
Receptor com Domínio Discoidina 1
Limite:
Feminino
/
Humanos
Idioma:
Chinês
Revista:
Acta Academiae Medicinae Sinicae
Ano de publicação:
2021
Tipo de documento:
Artigo