Coating with flexible DNA network enhanced T-cell activation and tumor killing for adoptive cell therapy

Ziyan ZHANG; Qiaojuan LIU; Jizhou TAN; Xiaoxia ZHAN; Ting LIU; Yuting WANG; Gen LU; Minhao WU; Yuanqing ZHANG

Ziyan ZHANG; Qiaojuan LIU; Jizhou TAN; Xiaoxia ZHAN; Ting LIU; Yuting WANG; Gen LU; Minhao WU; Yuanqing ZHANG.

Acta Pharmaceutica Sinica B ; (6): 1965-1977, 2021.

Article em En | WPRIM | ID: wpr-888845

Biblioteca responsável: WPRO

ABSTRACT

ABSTRACT

Adoptive cell therapy (ACT) is an emerging powerful cancer immunotherapy, which includes a complex process of genetic modification, stimulation and expansion. During these

Palavras-chave

Adoptive cell therapy; Cell surface engineering; DNA nanostructure; Rolling circle amplification; Selective cytoprotection; T cell; Tetrahedral DNA nanostructure; Tumor-killing

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Texto completo: 1 Base de dados: WPRIM Idioma: En Revista: Acta Pharmaceutica Sinica B Ano de publicação: 2021 Tipo de documento: Article

Texto completo

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Texto completo: 1 Base de dados: WPRIM Idioma: En Revista: Acta Pharmaceutica Sinica B Ano de publicação: 2021 Tipo de documento: Article