Up-to-date Knowledge on the Pathological Diagnosis of Hepatocellular Carcinoma / 대한소화기학회지
The Korean Journal of Gastroenterology
; : 268-283, 2021.
Article
em En
| WPRIM
| ID: wpr-918954
Biblioteca responsável:
WPRO
ABSTRACT
Hepatocellular carcinoma (HCC) has heterogeneous molecular and pathological features and biological behavior. Large-scale genetic studies of HCC were accumulated, and a pathological-molecular classification of HCC was proposed. Approximately 35% of HCCs can be classified into distinct histopathological subtypes according to their molecular characteristics. Among recently identified subtypes, macrotrabecular massive HCC, neutrophil-rich HCC, vessels encapsulating tumor clusters HCC, and progenitor phenotype HCC (HCC with CK19 expression) are associated with a poor prognosis, whereas the lymphocyte-rich HCC subtype is related to a better prognosis. This review provides up-to-date knowledge on the pathological diagnosis of HCC according to the updated World Health Organization Classification of Digestive System Tumors 5th ed.
Texto completo:
1
Base de dados:
WPRIM
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Idioma:
En
Revista:
The Korean Journal of Gastroenterology
Ano de publicação:
2021
Tipo de documento:
Article