Gene Mutation Types and Ethnic Distribution Characteristic of Thalassemia in Guiyang / 中国实验血液学杂志
Journal of Experimental Hematology
; (6): 1887-1891, 2021.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-922218
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE@#To investigate the genetic mutation types and ethnic distribution characteristics of thalassemia in Guiyang.@*METHODS@#The population underwent physical examination, antenatal examination and pre-pregnancy examination in our hospital from January 2019 to November 2019 was selected, and the thalassemia gene was detected by RDB-PCR.@*RESULTS@#Among the 4 572 samples, 346 were positive , and the total carrying rate was 7.57%. The carrying rate of α-thalassaemia gene was 5.42% (248 cases), while β-thalassemia was 1.99% (91 cases), and α+β-compound thalassemia was 0.15% (7 cases). α-thalassaemia genotype with the lack of right side -α@*CONCLUSION@#The gene types of thalassemia in Guiyang are complex and varied. The -α
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Etnicidade
/
China
/
Talassemia alfa
/
Minorias Étnicas e Raciais
/
Mutação
Limite:
Feminino
/
Humanos
/
Gravidez
País/Região como assunto:
Ásia
Idioma:
Chinês
Revista:
Journal of Experimental Hematology
Ano de publicação:
2021
Tipo de documento:
Artigo