Ligand-based substituent-anchoring design of selective receptor-interacting protein kinase 1 necroptosis inhibitors for ulcerative colitis therapy
Acta Pharmaceutica Sinica B
; (6): 3193-3205, 2021.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-922787
Biblioteca responsável:
WPRO
ABSTRACT
Receptor-interacting protein (RIP) kinase 1 is involved in immune-mediated inflammatory diseases including ulcerative colitis (UC) by regulating necroptosis and inflammation. Our group previously identified TAK-632 (
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Inglês
Revista:
Acta Pharmaceutica Sinica B
Ano de publicação:
2021
Tipo de documento:
Artigo
