Evaluation of Nutritional Status and Changes of Biochemical Parameters according to Protein Intake Levels in Hemodialysis Patients / 대한신장학회잡지

ABSTRACT

It is well recognized that malnutrition is one of the most important reversible factors contributing to mortality in hemodialysis patients. Until recently, highprotein diets were recommended for hemodialysis patients in an attempt to increase the synthesis of albumin and to promote the anabolism of body protein. However, the appropriateness of this recommendation has recently been questioned. This study investigated the effects of low and high protein intakes on the levels of serum albumin, total protein, BUN, and creatinine in 28 hemodialysis patients fed sequentially 1.0g(LPG) or 1.5g(HPG) protein and 30-35kcal/kg/ ideal body weight for four weeks. The HPG diet was associated with a significant increase in the levels of serum albumin, total protein, BUN, and creatinine however, the LPG diet was not. The serum levels of triglyceride and total cholesterol were in the normal range and did not changed by the diets. The levels of serum Hb, iron, and transferrin were lower than the normal values and did not changed by these two diets. Though individual considerations are recommended, it is possible that the high protein diet could increase the levels of serum albumin and total protein of the hemodialysis patients in Korea.