Research Progress of Immunotherapy for Non-small Cell Lung Cancer
with Drive Gene Mutation / 中国肺癌杂志
Chinese Journal of Lung Cancer
; (12): 201-206, 2022.
Article
em Zh
| WPRIM
| ID: wpr-928798
Biblioteca responsável:
WPRO
ABSTRACT
Lung cancer is the most lethal malignancy around the world and non-small cell lung cancer (NSCLC) accounts for 80% of all cases. Most of the NSCLC patients has "driver gene mutations" and targeted therapy achieved a relatively good efficacy, but some patients progressed or relapsed after treatment. Previous studies demonstrated that immune checkpoint inhibitor could improve the prognosis of advanced-stage NSCLC and prolong the survival time. However, the efficacy of immune therapy varies in NSCLC patients with different immune and molecular features. The efficacy of immune therapy was controversial in NSCLC patients with driver gene mutation. The present review will summarize the immune characteristics of NSCLC patients with driver mutation and the directions of immunotherapy for patients with driver mutation.
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Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Carcinoma Pulmonar de Células não Pequenas
/
Terapia de Alvo Molecular
/
Imunoterapia
/
Neoplasias Pulmonares
/
Mutação
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
Zh
Revista:
Chinese Journal of Lung Cancer
Ano de publicação:
2022
Tipo de documento:
Article