Relationship between iodine nutrition level and iodine content in drinking water in Weinan City, Shaanxi Province / 中华地方病学杂志

ABSTRACT

Objective:To explore the relationship between iodine nutrition level and iodine content in drinking water in Weinan City, Shaanxi Province.Methods:In 2017, in 10 counties (cities, districts) under the jurisdiction of Weinan City, one township (town, sub-district office, hereinafter referred to as the township) was selected in each county (city, district) according to the 5 directions of east, west, south, north, and middle. One primary school was selected in each township, and 42 children aged 8 to 10 (age and gender balanced) in each primary school were selected, urine samples and household edible salt samples were collected to test the contents of urinary iodine and salt iodine, and children's goiter was examined. Twenty-one pregnant women were selected from each township, urine samples and household edible salt samples were collected to test the contents of urinary iodine and salt iodine. At the same time, the drinking water samples of residents in townships were collected to test water iodine content. The correlation between urinary iodine, water iodine and salt iodine was analyzed by multiple linear regression.Results:Urine samples of 2 100 and 1 050 were collected from children and pregnant women, and the median urinary iodine was 254.51 and 172.55 μg/L, respectively. Edible salt samples of 2 100 and 1 050 were collected from children and pregnant women, and the median salt iodine was 24.00 and 24.44 mg/kg, respectively. A total of 232 water samples were collected, and the median water iodine was 26.53 μg/L. A total of 2 100 children's thyroids were examined, of which 65 had goiters, and the goiter rate was 3.10%. The regression model of urinary iodine and water iodine in children was statistically significant ( F = 6.48, P < 0.05), the multiple linear regression equation was = 235.52 + 1.01 x, coefficient of determination ( R2) = 0.119, 11.9% of the change of urinary iodine was related to the change of water iodine. Conclusions:Children's iodine nutrition in Weinan City is at an ultra-adequate level, while pregnant women's iodine nutrition is at an appropriate level. Eleven point nine percent of the changes in children's urinary iodine can be explained by the changes in water iodine.