Inhibitory actions of Pseuderanthemum palatiferum (Nees) Radlk. Leaf ethanolic extract and its phytochemicals against carbohydrate-digesting enzymes
Asian Pacific Journal of Tropical Biomedicine
; (12): 93-99, 2016.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-950804
Biblioteca responsável:
WPRO
ABSTRACT
Objective:
To investigate the effects of the leaf ethanolic extract of Pseuderanthemum palatiferum (PPE) and its isolated phytochemicals, stigmasterol and sitosterol-3-O-β-. d-glucopyranoside, against α-amylase and α-glucosidase enzyme activities both in vitro and in vivo.Methods:
A concentration of maltose, which is a product released in α-amylase-catalyzing reaction, was used as an index of in vitro α-amylase activity. Meanwhile, in vitro α-glucosidase enzyme activity was indicated by the amount of liberated p-nitrophenol in α-glucosidase-catalyzing reaction. In vivo α-amylase and α-glucosidase enzyme activities were evaluated in the normal rats by using oral starch tolerance test and oral sucrose tolerance test, respectively.Results:
PPE exerted a concentration-dependent inhibitory action against both α-amylase and α-glucosidase in vitro with the IC
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Asian Pacific Journal of Tropical Biomedicine
Ano de publicação:
2016
Tipo de documento:
Artigo