Classification and Diagnosis of Adult Glioma: A Scoping Review

ABSTRACT

Gliomas are primary central nervous system tumors that arise from glial progenitor cells.Gliomas have been classically classified morphologically based on their histopathological characteristics. However, with recent advances in cancer genomics, molecular profiles have now been integrated into the classification and diagnosis of gliomas. In this review article, we discuss the clinical features, imaging findings, and molecular profiles of adult-type diffuse gliomas based on the new 2021 World Health Organization Classifications of Tumors of the central nervous system.