Research Progress of Long Non-Coding RNA in Hematological Tumors --Review / 中国实验血液学杂志
Journal of Experimental Hematology
; (6): 306-310, 2023.
Article
em Zh
| WPRIM
| ID: wpr-971142
Biblioteca responsável:
WPRO
ABSTRACT
Long non-coding RNA (lncRNA) is a hot topic in the field of researching tumor pathogenesis, and the importance in hematologic malignancies has been gradually being elucidated. LncRNA not only regulates hematological tumorigenesis and progression through affecting various biological processes such as cell proliferation, differentiation, pluripotency and apoptosis; moreover, abnormal expression and mutation of lncRNA are closely related to drug resistance and prognosis. Thus lncRNA can be used as novel biomarker and potential therapeutic target for hematological tumors. In this review, we will focus on the latest progress of lncRNA in hematological tumors to provide new ideas for the clinical diagnosis, prognostic evaluation together with research and development of target drugs for hematologic malignancies.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Regulação Neoplásica da Expressão Gênica
/
Transformação Celular Neoplásica
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Neoplasias Hematológicas
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RNA Longo não Codificante
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Carcinogênese
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Neoplasias
Limite:
Humans
Idioma:
Zh
Revista:
Journal of Experimental Hematology
Ano de publicação:
2023
Tipo de documento:
Article