A case of two consecutive deliveries in a woman with acromegaly / 대한내과학회지
Korean Journal of Medicine
; : 662-666, 2004.
Article
em Ko
| WPRIM
| ID: wpr-97663
Biblioteca responsável:
WPRO
ABSTRACT
Acromegaly is a rare pituitary disorder and usually results from GH hypersecretion by a somatotroph adenoma. Disturbed pituitary function might lead to infertility or early pregnancy termination. Pregnancy in acromegaly is very rare. GH is a potent insulin antagonist, and pregnant patients with GH hypersecretion are prone to added glucose intolerance and diabetes. Pregnancy itself may impact the course of a pituitary tumor. In our case, pregnancy was uneventful and normal full-term infant was delivered at 1993 by vaginal delivery after transsphenoidal surgery and bromocriptine therapy. After delivery, GH and IGF-I level wasn't normalized. Postoperative pituitary MRI scan showed residual tumor. Therefore she received subsequent postoperative pituitary radiation (total dose : 5000 cGy). Next year, despite elevated GH and IGF-I, she delivered normal full-term infant. We report a case of two consecutive deliveries in a woman with acromegaly despite elevated GH and IGF-I levels after transsphenoidal surgery and radiation therapy.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Doenças da Hipófise
/
Neoplasias Hipofisárias
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Acromegalia
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Fator de Crescimento Insulin-Like I
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Hormônio do Crescimento
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Imageamento por Ressonância Magnética
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Bromocriptina
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Intolerância à Glucose
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Neoplasia Residual
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Adenoma Hipofisário Secretor de Hormônio do Crescimento
Limite:
Female
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Humans
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Infant
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Pregnancy
Idioma:
Ko
Revista:
Korean Journal of Medicine
Ano de publicação:
2004
Tipo de documento:
Article