Diagnostic methods for peritoneal molecular residual disease in gastric cancer / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery
; (12): 419-422, 2023.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-986808
Biblioteca responsável:
WPRO
ABSTRACT
Peritoneal metastasis of gastric cancer serving as the most frequent form of metastasis, is one of the leading causes of death. A portion of surgically treated patients often suffer from small peritoneal residual metastasis, which will lead to recurrence and metastasis of gastric cancer patients after surgery. Given these, the prevention and treatment of peritoneal metastasis of gastric cancer deserves more attention. Molecular residual disease (MRD) refers to the molecular abnormalities of tumor origin that cannot be found by traditional imaging or other laboratory methods after treatment, but can be found by liquid biopsy, representing the possibility of tumor persistence or clinical progress. In recent years, the detection of MRD based on ctDNA has gradually become a research hotspot in the prevention and treatment of peritoneal metastasis. Our team established a new method for MRD molecular diagnosis of gastric cancer, and reviewed the research achievements in this field.
Texto completo:
Disponível
Contexto em Saúde:
ODS3 - Meta 3.4 Reduzir as mortes prematuras devido doenças não transmissíveis
Problema de saúde:
Doenças do Sistema Digestório
/
Outras Neoplasias Malignas
/
Neoplasia do Estômago
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Neoplasias Peritoneais
/
Neoplasias Gástricas
/
Neoplasia Residual
/
Biópsia Líquida
Limite:
Humanos
Idioma:
Chinês
Revista:
Chinese Journal of Gastrointestinal Surgery
Ano de publicação:
2023
Tipo de documento:
Artigo