Recent advances in small-molecule inhibitors targeting influenza virus glycoproteins / 药学学报
Acta Pharmaceutica Sinica
; (12): 3254-3269, 2023.
Article
em Zh
| WPRIM
| ID: wpr-999070
Biblioteca responsável:
WPRO
ABSTRACT
Hemagglutinin and neuraminidase, two important glycoproteins on the surface of influenza virus, play a considerable role in the entry and release stage of the viral life cycle, respectively. With in-depth investigation of influenza virus glycoproteins and the continuous innovation of drug discovery strategies, a new generation of glycoproteins inhibitors have been continuously discovered. From the point of view of medicinal chemistry, this review summarizes the current advances in seeking small-molecule inhibitors targeting influenza virus glycoproteins, hoping to provide valuable guidance for future development of novel antiviral drugs.
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Base de dados:
WPRIM
Idioma:
Zh
Revista:
Acta Pharmaceutica Sinica
Ano de publicação:
2023
Tipo de documento:
Article