Detalhe da pesquisa
1.
A dedicated flavin-dependent monooxygenase catalyzes the hydroxylation of demethoxyubiquinone into ubiquinone (coenzyme Q) in Arabidopsis.
J Biol Chem
; 297(5): 101283, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34626646
2.
COQ11 deletion mitigates respiratory deficiency caused by mutations in the gene encoding the coenzyme Q chaperone protein Coq10.
J Biol Chem
; 295(18): 6023-6042, 2020 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32205446
3.
ADCK4 Deficiency Destabilizes the Coenzyme Q Complex, Which Is Rescued by 2,4-Dihydroxybenzoic Acid Treatment.
J Am Soc Nephrol
; 31(6): 1191-1211, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32381600
4.
The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR.
Nature
; 510(7505): 397-401, 2014 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-24828042
5.
Treatment with 2,4-Dihydroxybenzoic Acid Prevents FSGS Progression and Renal Fibrosis in Podocyte-Specific Coq6 Knockout Mice.
J Am Soc Nephrol
; 30(3): 393-405, 2019 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-30737270
6.
Metabolism of the Flavonol Kaempferol in Kidney Cells Liberates the B-ring to Enter Coenzyme Q Biosynthesis.
Molecules
; 25(13)2020 Jun 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32605010
7.
Human COQ10A and COQ10B are distinct lipid-binding START domain proteins required for coenzyme Q function.
J Lipid Res
; 60(7): 1293-1310, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31048406
8.
Chromatin-remodeling SWI/SNF complex regulates coenzyme Q6 synthesis and a metabolic shift to respiration in yeast.
J Biol Chem
; 292(36): 14851-14866, 2017 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28739803
9.
Identification of Coq11, a new coenzyme Q biosynthetic protein in the CoQ-synthome in Saccharomyces cerevisiae.
J Biol Chem
; 290(12): 7517-34, 2015 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25631044
10.
Yeast Coq9 controls deamination of coenzyme Q intermediates that derive from para-aminobenzoic acid.
Biochim Biophys Acta
; 1851(9): 1227-39, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26008578
11.
Biochemistry: Unexpected role for vitamin B2.
Nature
; 522(7557): 427-8, 2015 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26083748
12.
Resveratrol and para-coumarate serve as ring precursors for coenzyme Q biosynthesis.
J Lipid Res
; 56(4): 909-19, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25681964
13.
Coenzyme Q supplementation or over-expression of the yeast Coq8 putative kinase stabilizes multi-subunit Coq polypeptide complexes in yeast coq null mutants.
Biochim Biophys Acta
; 1841(4): 630-44, 2014 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-24406904
14.
Molecular characterization of the human COQ5 C-methyltransferase in coenzyme Q10 biosynthesis.
Biochim Biophys Acta
; 1841(11): 1628-38, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25152161
15.
A conserved START domain coenzyme Q-binding polypeptide is required for efficient Q biosynthesis, respiratory electron transport, and antioxidant function in Saccharomyces cerevisiae.
Biochim Biophys Acta
; 1831(4): 776-791, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23270816
16.
Unusual kinetic isotope effects of deuterium reinforced polyunsaturated fatty acids in tocopherol-mediated free radical chain oxidations.
J Am Chem Soc
; 136(3): 838-41, 2014 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24380377
17.
Overexpression of the Coq8 kinase in Saccharomyces cerevisiae coq null mutants allows for accumulation of diagnostic intermediates of the coenzyme Q6 biosynthetic pathway.
J Biol Chem
; 287(28): 23571-81, 2012 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-22593570
18.
Focal segmental glomerulosclerosis is associated with a PDSS2 haplotype and, independently, with a decreased content of coenzyme Q10.
Am J Physiol Renal Physiol
; 305(8): F1228-38, 2013 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23926186
19.
Folate status of gut microbiome affects Caenorhabditis elegans lifespan.
BMC Biol
; 10: 66, 2012 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-22849295
20.
New Insights on the Uptake and Trafficking of Coenzyme Q.
Antioxidants (Basel)
; 12(7)2023 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37507930