Detalhe da pesquisa
1.
Discovery of a small molecule RXFP3/4 agonist that increases food intake in rats upon acute central administration.
Bioorg Med Chem Lett
; 29(8): 991-994, 2019 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30824200
2.
Discovery of 1-((6-Aminopyridin-3-yl)Methyl)-3-(4-Bromophenyl)Urea as a Potent, Irreversible Myeloperoxidase Inhibitor.
J Pharmacol Exp Ther
; 367(1): 147-154, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30076263
3.
Identification and characterization of a phenyl-thiazolyl-benzoic acid derivative as a novel RAR/RXR agonist.
Heliyon
; 5(11): e02849, 2019 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-31768440
4.
Pharmacological profiling of a dual FAK/IGF-1R kinase inhibitor TAE226 in cellular and in vivo tumor models.
BMC Res Notes
; 12(1): 347, 2019 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31215459
5.
Blood Pressure-Associated Genetic Variants in the Natriuretic Peptide Receptor 1 Gene Modulate Guanylate Cyclase Activity.
Circ Genom Precis Med
; 12(8): e002472, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31430210
6.
Tumor growth inhibition by synthetic and expressed siRNA targeting focal adhesion kinase.
Int J Oncol
; 33(1): 215-24, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18575768
7.
[Effect of TRK-820, a selective kappa opioid receptor agonist, on scratching behavior in an animal model of atopic dermatitis].
Nihon Shinkei Seishin Yakurigaku Zasshi
; 28(2): 75-83, 2008 Apr.
Artigo
em Japonês
| MEDLINE | ID: mdl-18516986
8.
Inhibition of both focal adhesion kinase and insulin-like growth factor-I receptor kinase suppresses glioma proliferation in vitro and in vivo.
Mol Cancer Ther
; 6(4): 1357-67, 2007 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-17431114
9.
Involvement of central mu-opioid system in the scratching behavior in mice, and the suppression of it by the activation of kappa-opioid system.
Eur J Pharmacol
; 477(1): 29-35, 2003 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-14512095
10.
Antipruritic activity of the kappa-opioid receptor agonist, TRK-820.
Eur J Pharmacol
; 435(2-3): 259-64, 2002 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-11821035
11.
In vitro and in vivo pharmacological characterization of the main metabolites of nalfurafine hydrochloride.
Eur J Pharmacol
; 695(1-3): 57-61, 2012 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22981641
12.
Silencing of focal adhesion kinase by tumor direct injection of small interfering RNA decreases in vivo tumor growth.
Cancer Biol Ther
; 8(13): 1292-9, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19458494
13.
Therapeutic efficacy of a novel focal adhesion kinase inhibitor TAE226 in ovarian carcinoma.
Cancer Res
; 67(22): 10976-83, 2007 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18006843
14.
Design and synthesis of 7H-pyrrolo[2,3-d]pyrimidines as focal adhesion kinase inhibitors. Part 2.
Bioorg Med Chem Lett
; 16(10): 2689-92, 2006 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16524731