Detalhe da pesquisa
1.
Accurate de novo design of membrane-traversing macrocycles.
Cell
; 185(19): 3520-3532.e26, 2022 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36041435
2.
Computationally designed peptide macrocycle inhibitors of New Delhi metallo-ß-lactamase 1.
Proc Natl Acad Sci U S A
; 118(12)2021 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33723038
3.
Heme redox potentials hold the key to reactivity differences between nitric oxide reductase and heme-copper oxidase.
Proc Natl Acad Sci U S A
; 115(24): 6195-6200, 2018 06 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29802230
4.
Design of a single protein that spans the entire 2-V range of physiological redox potentials.
Proc Natl Acad Sci U S A
; 113(2): 262-7, 2016 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-26631748
5.
Design and fine-tuning redox potentials of metalloproteins involved in electron transfer in bioenergetics.
Biochim Biophys Acta
; 1857(5): 557-581, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26301482
6.
Stopped-Flow Studies of the Reduction of the Copper Centers Suggest a Bifurcated Electron Transfer Pathway in Peptidylglycine Monooxygenase.
Biochemistry
; 55(13): 2008-21, 2016 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26982589
7.
Enhancing Mn(II)-Binding and Manganese Peroxidase Activity in a Designed Cytochrome c Peroxidase through Fine-Tuning Secondary-Sphere Interactions.
Biochemistry
; 55(10): 1494-502, 2016 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26885726
8.
A Purple Cupredoxin from Nitrosopumilus maritimus Containing a Mononuclear Type 1 Copper Center with an Open Binding Site.
J Am Chem Soc
; 138(20): 6324-7, 2016 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-27120678
9.
Biochemical and Biophysical Understanding of Metal Ion Selectivity of DNAzymes.
Inorganica Chim Acta
; 452: 12-24, 2016 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27695134
10.
Defining the role of tyrosine and rational tuning of oxidase activity by genetic incorporation of unnatural tyrosine analogs.
J Am Chem Soc
; 137(14): 4594-7, 2015 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25672571
11.
Identifying the elusive sites of tyrosyl radicals in cytochrome c peroxidase: implications for oxidation of substrates bound at a site remote from the heme.
Biochemistry
; 53(23): 3781-9, 2014 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-24901481
12.
Direct EPR observation of a tyrosyl radical in a functional oxidase model in myoglobin during both H2O2 and O2 reactions.
J Am Chem Soc
; 136(4): 1174-1177, 2014 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-24383850
13.
Osthole attenuated cytotoxicity induced by 6-OHDA in SH-SY5Y cells through inhibition of JAK/STAT and MAPK pathways.
Iran J Basic Med Sci
; 26(8): 953-959, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37427324
14.
Macrocyclic Octapeptide Binding and Inferences on Protein Substrate Binding to Histone Deacetylase 6.
ACS Chem Biol
; 18(4): 959-968, 2023 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37027789
15.
Impedimetric Sensing: An Emerging Tool for Combating the COVID-19 Pandemic.
Biosensors (Basel)
; 13(2)2023 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36831970
16.
Identification of pseudobaptigenin as a novel polyphenol-based multi-target antagonist of different hormone receptors for breast cancer therapeutics.
J Biomol Struct Dyn
; : 1-13, 2023 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37409735
17.
Moderate-Affinity Affibodies Modulate the Delivery and Bioactivity of Bone Morphogenetic Protein-2.
Adv Healthc Mater
; 12(26): e2300793, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37379021
18.
Design and structural validation of peptide-drug conjugate ligands of the kappa-opioid receptor.
Nat Commun
; 14(1): 8064, 2023 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38052802
19.
Computational Design of Structured and Functional Peptide Macrocycles.
Methods Mol Biol
; 2371: 63-100, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-34596844
20.
Design of Protein Segments and Peptides for Binding to Protein Targets.
Biodes Res
; 2022: 9783197, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-37850124