Detalhe da pesquisa
1.
Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting TGF-ß and PD-L1, in Patients With Non-Small Cell Lung Cancer Resistant or Refractory to Immune Checkpoint Inhibitors.
Oncologist
; 28(3): 258-267, 2023 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36571770
2.
Connective Tissue Growth Factor Domain 4 Amplifies Fibrotic Kidney Disease through Activation of LDL Receptor-Related Protein 6.
J Am Soc Nephrol
; 28(6): 1769-1782, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28130402
3.
Global remodeling of nucleosome positions in C. elegans.
BMC Genomics
; 14: 284, 2013 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-23622142
4.
High-throughput sequencing reveals a simple model of nucleosome energetics.
Proc Natl Acad Sci U S A
; 107(49): 20998-1003, 2010 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21084631
5.
Risk assessment of drug-drug interaction potential for bintrafusp alfa with cytochrome P4503A4 substrates: A totality of evidence approach.
Clin Transl Sci
; 15(12): 2838-2843, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36152313
6.
Identification of HMGA2 as a predictive biomarker of response to bintrafusp alfa in a phase 1 trial in patients with advanced triple-negative breast cancer.
Front Oncol
; 12: 981940, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36568239
7.
Colocalized targeting of TGF-ß and PD-L1 by bintrafusp alfa elicits distinct antitumor responses.
J Immunother Cancer
; 10(7)2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35858707
8.
Simultaneous targeting of TGF-ß/PD-L1 synergizes with radiotherapy by reprogramming the tumor microenvironment to overcome immune evasion.
Cancer Cell
; 39(10): 1388-1403.e10, 2021 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34506739
9.
Enhanced preclinical antitumor activity of M7824, a bifunctional fusion protein simultaneously targeting PD-L1 and TGF-ß.
Sci Transl Med
; 10(424)2018 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29343622
10.
A Biophysical Approach to Predicting Protein-DNA Binding Energetics.
Genetics
; 200(4): 1349-61, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26081193
11.
Characteristics of ventricular shunt malfunctions among patients with neurocysticercosis.
Neurosurgery
; 50(4): 757-61; discussion 761-2, 2002 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-11904026
12.
Statistical mechanics of nucleosome ordering by chromatin-structure-induced two-body interactions.
Phys Rev E Stat Nonlin Soft Matter Phys
; 83(5 Pt 1): 050903, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21728479