Detalhe da pesquisa
1.
Exploring switch II pocket conformation of KRAS(G12D) with mutant-selective monobody inhibitors.
Proc Natl Acad Sci U S A
; 120(28): e2302485120, 2023 07 11.
Artigo
Inglês
| MEDLINE | ID: mdl-37399416
2.
Single Mutation on Trastuzumab Modulates the Stability of Antibody-Drug Conjugates Built Using Acetal-Based Linkers and Thiol-Maleimide Chemistry.
J Am Chem Soc
; 144(12): 5284-5294, 2022 03 30.
Artigo
Inglês
| MEDLINE | ID: mdl-35293206
3.
One-pot stapling of interchain disulfides of antibodies using an isobutylene motif.
Org Biomol Chem
; 17(7): 2005-2012, 2019 02 13.
Artigo
Inglês
| MEDLINE | ID: mdl-30539956
4.
Chemoselective Installation of Amine Bonds on Proteins through Aza-Michael Ligation.
J Am Chem Soc
; 139(50): 18365-18375, 2017 12 20.
Artigo
Inglês
| MEDLINE | ID: mdl-29206031
5.
Creating MHC-Restricted Neoantigens with Covalent Inhibitors That Can Be Targeted by Immune Therapy.
Cancer Discov
; 13(1): 132-145, 2023 01 09.
Artigo
Inglês
| MEDLINE | ID: mdl-36250888
6.
CD98hc is a target for brain delivery of biotherapeutics.
Nat Commun
; 14(1): 5053, 2023 08 19.
Artigo
Inglês
| MEDLINE | ID: mdl-37598178
7.
Cleavable cationic antibacterial amphiphiles: synthesis, mechanism of action, and cytotoxicities.
Langmuir
; 28(33): 12225-34, 2012 Aug 21.
Artigo
Inglês
| MEDLINE | ID: mdl-22838496
8.
Monobodies as tool biologics for accelerating target validation and druggable site discovery.
RSC Med Chem
; 12(11): 1839-1853, 2021 Nov 17.
Artigo
Inglês
| MEDLINE | ID: mdl-34820623
9.
NRARP displays either pro- or anti-tumoral roles in T-cell acute lymphoblastic leukemia depending on Notch and Wnt signaling.
Oncogene
; 39(5): 975-986, 2020 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31586130
10.
IL-7R-mediated signaling in T-cell acute lymphoblastic leukemia: An update.
Adv Biol Regul
; 71: 88-96, 2019 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30249539
11.
Efficient and irreversible antibody-cysteine bioconjugation using carbonylacrylic reagents.
Nat Protoc
; 14(1): 86-99, 2019 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30470819
12.
A fully human anti-IL-7Rα antibody promotes antitumor activity against T-cell acute lymphoblastic leukemia.
Leukemia
; 33(9): 2155-2168, 2019 09.
Artigo
Inglês
| MEDLINE | ID: mdl-30850736
13.
Machine intelligence decrypts ß-lapachone as an allosteric 5-lipoxygenase inhibitor.
Chem Sci
; 9(34): 6899-6903, 2018 Sep 14.
Artigo
Inglês
| MEDLINE | ID: mdl-30310622
14.
Author Correction: CD98hc is a target for brain delivery of biotherapeutics.
Nat Commun
; 14(1): 5516, 2023 Sep 07.
Artigo
Inglês
| MEDLINE | ID: mdl-37679403
15.
From the outside, from within: Biological and therapeutic relevance of signal transduction in T-cell acute lymphoblastic leukemia.
Cell Signal
; 38: 10-25, 2017 10.
Artigo
Inglês
| MEDLINE | ID: mdl-28645565
16.
A Biodegradable Polycationic Paint that Kills Bacteria in Vitro and in Vivo.
ACS Appl Mater Interfaces
; 8(43): 29298-29309, 2016 Nov 02.
Artigo
Inglês
| MEDLINE | ID: mdl-27709890
17.
Glycopeptide Antibiotic To Overcome the Intrinsic Resistance of Gram-Negative Bacteria.
ACS Infect Dis
; 2(2): 132-9, 2016 02 12.
Artigo
Inglês
| MEDLINE | ID: mdl-27624964
18.
Construction of homogeneous antibody-drug conjugates using site-selective protein chemistry.
Chem Sci
; 7(5): 2954-2963, 2016 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29997785
19.
Broad spectrum antibacterial and antifungal polymeric paint materials: synthesis, structure-activity relationship, and membrane-active mode of action.
ACS Appl Mater Interfaces
; 7(3): 1804-15, 2015 Jan 28.
Artigo
Inglês
| MEDLINE | ID: mdl-25541751
20.
Membrane active vancomycin analogues: a strategy to combat bacterial resistance.
J Med Chem
; 57(11): 4558-68, 2014 Jun 12.
Artigo
Inglês
| MEDLINE | ID: mdl-24846441