Detalhe da pesquisa
1.
Ketone bodies supplementation restores the barrier function, induces a metabolic switch, and elicits beta-hydroxybutyrate diffusion across a monolayer of iPSC-derived brain microvascular endothelial cells.
Microvasc Res
; 150: 104585, 2023 11.
Artigo
Inglês
| MEDLINE | ID: mdl-37437687
2.
Human-Induced Pluripotent Stem Cell-Based Model of the Blood-Brain at 10 Years: A Retrospective on Past and Current Disease Models.
Handb Exp Pharmacol
; 281: 141-156, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-36943490
3.
Comparative study of expression and activity of glucose transporters between stem cell-derived brain microvascular endothelial cells and hCMEC/D3 cells.
Am J Physiol Cell Physiol
; 313(4): C421-C429, 2017 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28993322
4.
Analysis of Cancer-Targeting Alkylphosphocholine Analogue Permeability Characteristics Using a Human Induced Pluripotent Stem Cell Blood-Brain Barrier Model.
Mol Pharm
; 13(9): 3341-9, 2016 09 06.
Artigo
Inglês
| MEDLINE | ID: mdl-27421304
5.
Hypoxia selectively disrupts brain microvascular endothelial tight junction complexes through a hypoxia-inducible factor-1 (HIF-1) dependent mechanism.
J Cell Physiol
; 229(8): 1096-105, 2014 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-24375098
6.
In Vitro Models of the Human Blood-Brain Barrier Utilising Human Induced Pluripotent Stem Cells: Opportunities and Challenges.
Methods Mol Biol
; 2492: 53-72, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35733038
7.
Abeta peptides disrupt the barrier integrity and glucose metabolism of human induced pluripotent stem cell-derived brain microvascular endothelial cells.
Neurotoxicology
; 89: 110-120, 2022 03.
Artigo
Inglês
| MEDLINE | ID: mdl-35065085
8.
Perlecan domain V modulates astrogliosis in vitro and after focal cerebral ischemia through multiple receptors and increased nerve growth factor release.
Glia
; 59(12): 1822-40, 2011 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-21850672
9.
Presence of a mutation in PSEN1 or PSEN2 gene is associated with an impaired brain endothelial cell phenotype in vitro.
Fluids Barriers CNS
; 18(1): 3, 2021 Jan 07.
Artigo
Inglês
| MEDLINE | ID: mdl-33413468
10.
Neurolysin substrates bradykinin, neurotensin and substance P enhance brain microvascular permeability in a human in vitro model.
J Neuroendocrinol
; 33(2): e12931, 2021 02.
Artigo
Inglês
| MEDLINE | ID: mdl-33506602
11.
Hyaluronan impairs the barrier integrity of brain microvascular endothelial cells through a CD44-dependent pathway.
J Cereb Blood Flow Metab
; 39(9): 1759-1775, 2019 09.
Artigo
Inglês
| MEDLINE | ID: mdl-29589805
12.
Cerebral hypoxia/ischemia selectively disrupts tight junctions complexes in stem cell-derived human brain microvascular endothelial cells.
Fluids Barriers CNS
; 13(1): 16, 2016 Oct 11.
Artigo
Inglês
| MEDLINE | ID: mdl-27724968