Detalhe da pesquisa
1.
Dexmedetomidine Clearance Decreases with Increasing Drug Exposure: Implications for Current Dosing Regimens and Target-controlled Infusion Models Assuming Linear Pharmacokinetics.
Anesthesiology
; 136(2): 279-292, 2022 02 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34851425
2.
Breathing variability-implications for anaesthesiology and intensive care.
Crit Care
; 25(1): 280, 2021 08 05.
Artigo
Inglês
| MEDLINE | ID: mdl-34353348
3.
Mathematical modeling of the glucagon challenge test.
J Pharmacokinet Pharmacodyn
; 46(6): 553-564, 2019 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-31571122
4.
Reversal of mecamylamine-induced effects in healthy subjects by nicotine receptor agonists: Cognitive and (electro) physiological responses.
Br J Clin Pharmacol
; 84(5): 888-899, 2018 05.
Artigo
Inglês
| MEDLINE | ID: mdl-29319910
5.
An anti-nicotinic cognitive challenge model using mecamylamine in comparison with the anti-muscarinic cognitive challenge using scopolamine.
Br J Clin Pharmacol
; 83(8): 1676-1687, 2017 08.
Artigo
Inglês
| MEDLINE | ID: mdl-28217868
6.
Model-based exposure-response analysis to quantify age related differences in the response to scopolamine in healthy subjects.
Br J Clin Pharmacol
; 82(4): 1011-21, 2016 10.
Artigo
Inglês
| MEDLINE | ID: mdl-27273555
7.
No synergistic effect of subtherapeutic doses of donepezil and EVP-6124 in healthy elderly subjects in a scopolamine challenge model.
Alzheimers Dement (N Y)
; 5: 89-98, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-30984817
8.
A Computerized Test Battery to Study Pharmacodynamic Effects on the Central Nervous System of Cholinergic Drugs in Early Phase Drug Development.
J Vis Exp
; (144)2019 02 11.
Artigo
Inglês
| MEDLINE | ID: mdl-30799845
9.
Pharmacokinetics and pharmacodynamics of oral mecamylamine - development of a nicotinic acetylcholine receptor antagonist cognitive challenge test using modelling and simulation.
J Psychopharmacol
; 31(2): 192-203, 2017 02.
Artigo
Inglês
| MEDLINE | ID: mdl-27927703
10.
EEG machine learning for accurate detection of cholinergic intervention and Alzheimer's disease.
Sci Rep
; 7(1): 5775, 2017 07 18.
Artigo
Inglês
| MEDLINE | ID: mdl-28720796
11.
Pharmacotherapy in pediatric epilepsy: from trial and error to rational drug and dose selection - a long way to go.
Expert Opin Drug Metab Toxicol
; 12(10): 1143-56, 2016 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-27434782
12.
Post-burn hypertrophic scars are characterized by high levels of IL-1ß mRNA and protein and TNF-α type I receptors.
Burns
; 38(5): 668-76, 2012 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-22226222
13.
Heparina en quemaduras de segundo grado profundo en un modelo murino / Heparin in a deep second degree burn in a murine model
Cir. gen
; 33(2): 86-90, abr.-jun. 2011. ilus
Artigo
Espanhol
| LILACS | ID: lil-706840