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1.
J Dairy Res ; 88(4): 440-444, 2021 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-35067239

RESUMO

The objective of this study was to examine the foaming properties of sodium caseinates (Na-cas) extracted from bovine and camel fresh milks after heating at 70, 80, 90 and 100°C for 30 min at laboratory scale. Experimental results indicated that greater foam was obtained with camel Na-cas than with bovine Na-cas at all heating temperatures due to the higher ß-casein content in camel caseins (~53.4% of total proteins, RP-HPLC results). Increasing heat-treatment temperature to 100°C significantly enhanced the foaming properties by raising surface hydrophobicity and decreasing electronegative charge as well as interfacial tension values upon heating. This study concluded that camel Na-cas has important foaming properties in agricultural and food industries.


Assuntos
Camelus , Caseínas , Animais , Bovinos , Temperatura Alta , Leite , Temperatura
2.
BMC Surg ; 21(1): 46, 2021 Jan 20.
Artigo em Inglês | MEDLINE | ID: mdl-33472623

RESUMO

BACKGROUND: This study aims to describe the clinical features of the isolated primitive splenic hydatid cyst, discuss and compare the different surgical approaches of this uncommon disease. METHODS: This is a descriptive retrospective study carried out over a period of 7 years extending from January 2013 to December 2019 reporting eight cases of isolated primitive splenic hydatid cysts. Data were collected from the register of the general surgery department of the Jendouba regional hospital. Files concerning another associated hydatid localization were excluded. Four patients underwent total splenectomy and four of them underwent different spleen preserving surgical techniques including resection of the protruding dome, partial splenectomy and pericystectomy. RESULTS: The diagnosis was incidentally made in 50% of cases. The main other revealing complaints are pain in the left upper quadrant of abdomen in 25% of cases and a painless renitent mass in the same quadrant in only 12,5%. None of patients who underwent total splenectomy had fever or sings of postoperative sepsis. Compared to those who had total splenectomy, patients who underwent spleen preserving surgery had a longer average hospital stay (9 vs 6,25 days) related to post-operative complications including abscess in the residual cavity after protruding dome resection in one patient and post-operative haemorrhage in one patient. CONCLUSIONS: The current case series argues in favor of total splenectomy, preferably by laparoscopic route whenever the technical platform allows it, associated with some specific peri-operative therapeutic measures. It seems to be the safest way that helps to avoid post-operative complications of spleen saving surgical modalities. These complications are usually difficult to manage in poor countries with limited technical resources. Total splenectomy guarantees at least a decreased hospital stay, reduced healthcare costs, and the absence of recurrence in highly endemic underdeveloped countries.


Assuntos
Equinococose/cirurgia , Esplenectomia/efeitos adversos , Adolescente , Adulto , Ensaio de Imunoadsorção Enzimática , Humanos , Pessoa de Meia-Idade , Estudos Retrospectivos , Resultado do Tratamento , Adulto Jovem
3.
Environ Monit Assess ; 192(7): 442, 2020 Jun 17.
Artigo em Inglês | MEDLINE | ID: mdl-32556648

RESUMO

Groundwater (GW) artificial recharge with treated wastewater (TWW) is seen as a promising technical solution to overcome groundwater overexploitation and seawater intrusion and to ascertain future water resources availability. While these introduced recharge systems have shown positive impacts in many areas across the world, their effective contribution to GW recharge is still not well quantified in water-stressed regions such as Tunisia. The scarcity of on-site data with accurate temporal and spatial measurements and resolution in such areas hinders the clear assessment of these recharge systems' performances. This article presents an approach based on the on-site monitoring of groundwater level and salinity measurements and recharge rate records spanning over the 6-year period to investigate the performances of a wastewater-based recharge system located in the Korba-El Mida site in Tunisia. The analysis showed that the artificial recharge did not have an impact on groundwater level. Controversially, a decrease in water salinity in and around the study site was observed. Findings emphasize on the weak wastewater volumes applied to the recharge system and the clogging phenomena that occurred in the pool and in the vadose zone. Furthermore, analyzing the information over a short period of time could be misleading as the results of a 6-year period of monitoring show clearly that the way the site was managed and the local conditions have a role in understanding and interpreting the results even if the artificial recharge was appropriately designed.


Assuntos
Monitoramento Ambiental , Água Subterrânea , Água do Mar , Tunísia , Recursos Hídricos
4.
Toxicol Ind Health ; 35(8): 558-566, 2019 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-31462195

RESUMO

The absence of studies that investigate the causes and risk factors of nonfatal occupational injury in Tunisia inhibits the development of effective preventive strategies. The objective of this study was to identify the causes and risk factors of nonfatal occupational injury in the private sector in Tunisia. We used retrospective data derived from the occupational injury reporting forms submitted to the Caisse Nationale d'Assurance Maladie. A sample of 42,293 workers in the private sector for 2014 contains information on sociodemographic variables. Multivariable Poisson regression was used to investigate the association of cause-specific injury with demographic variables. The leading causes of nonfatal occupational injury were "falls" (employee fall and falling objects; 36%) and "struck by objects" (23%). Male employees were at higher risk of "exposure to extreme temperatures" (PR = 12 [7-45]), "asphyxia and poisoning" (PR = 4 [2.4-12]), "transport and handling" (PR = 2.4 [1.9-5]), "falling objects" (PR = 2.3 [1.4-3.7]), and "employee fall" (PR = 1.2 [1.1-1.5]). Although, rural areas were at higher risk to "asphyxia and poisoning" (PR = 3.6 [1.1-11.4]), "transport and handling" (PR = 2.5 [1.3-5.4]), and "burns" (PR = 1.3 [1.1-3]). It is important that effective interventions be developed to minimize the impact of falls and "struck by objects." The most vulnerable categories to occupational injury are less educated men, rural residents aged between 15 years and 24 years, and elderly employees (55 years and over). Thus, our findings can contribute to the planning of prevention intervention programs that should expand to the most vulnerable categories.


Assuntos
Traumatismos Ocupacionais/etiologia , Acidentes por Quedas/estatística & dados numéricos , Acidentes de Trabalho/estatística & dados numéricos , Adolescente , Adulto , Fatores Etários , Asfixia/epidemiologia , Asfixia/etiologia , Estudos Transversais , Feminino , Golpe de Calor/epidemiologia , Golpe de Calor/etiologia , Humanos , Masculino , Pessoa de Meia-Idade , Traumatismos Ocupacionais/epidemiologia , Intoxicação/epidemiologia , Intoxicação/etiologia , Distribuição de Poisson , Setor Privado/estatística & dados numéricos , Fatores de Risco , Fatores Sexuais , Fatores Socioeconômicos , Tunísia/epidemiologia , Adulto Jovem
5.
Fish Physiol Biochem ; 41(6): 1587-96, 2015 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-26242460

RESUMO

The objective of this study was to determine the effect of two levels of inclusion of xylan oligosaccharides (XOS) extracted from corncob on growth, feed utilization, immune status and disease resistance of Mediterranean sea bass (Dicentrarchus labrax) fingerlings. Specimens of 4.75 ± 0.69 g at initial density of 2.7 ± 0.13 kg/m(3) were fed during 12 weeks at 0 g kg(-1) diet, 5 g kg(-1) diet and 10 g kg(-1) diet, dietary XOS level of inclusion in a commercial sea bass diet. Feeding the fish at both XOS dietary inclusion levels significantly increased weight gain, protein efficiency ratio and feed conversion ratio. Feeding of supplemented diets to fish led to reducing mortalities after challenging with A. hydrophila. The haematological and immunological parameters were assayed in both pre-challenged and post-challenged groups. There was an increased trend in red blood corpuscles, white blood corpuscles, pack cell volume, haemoglobin (Hb %) and serum protein content in treated groups over the control as time elapsed with the feeding trials. The serum immunoglobulin level and lysozyme activity showed an increased trend in the fed groups. Histological features of the liver showed lower lipid vacuolization and regular-shaped morphology of hepatocytes around the sinusoidal spaces denoting a better utilization of dietary nutrients supported with the morphometric data. In conclusion, XOS added at a designated dose (5 g kg(-1) diet) in the diet improves growth and stimulates the immunity and makes D. labrax fingerlings more resistant to infection by A. hydrophila.


Assuntos
Ração Animal/análise , Bass/crescimento & desenvolvimento , Suplementos Nutricionais , Xilanos/química , Fenômenos Fisiológicos da Nutrição Animal , Animais , Bass/imunologia , Proteínas Sanguíneas/análise , Contagem de Eritrócitos , Hemoglobinas/análise , Hepatócitos/citologia , Imunidade Inata , Imunoglobulinas/sangue , Contagem de Leucócitos , Fígado/crescimento & desenvolvimento , Muramidase/sangue , Zea mays/química
6.
J Eval Clin Pract ; 2024 May 26.
Artigo em Inglês | MEDLINE | ID: mdl-38796771

RESUMO

BACKGROUND: Oncology nurses constantly provide emotional support to patients and are confronted with their suffering, which represents chronic stress leading to the development of burnout syndrome. AIM: This study aimed to evaluate the prevalence of burnout and identify associated factors in a sample of oncology nurses. METHODS: We conducted a descriptive cross-sectional study with 70 oncology nurses at the Salah Azaiez Institute of Oncology in Tunisia. Burnout was assessed using the Maslach Burnout Inventory Human Service Survey. This study follows the STrengthening the Reporting of OBservational studies in Epidemiology (STROBE) Guidelines. RESULTS: Burnout affected 60 nurses (85.7%), with a high level in 20% of cases. High scores of emotional exhaustion, depersonalisation, and low personal accomplishment were recorded in 65.7%, 50% and 25.7% respectively. Emotional exhaustion was associated with higher age, marital status, having 2 or 3 or more dependent children, number of patients under care exceeding 15, professional experience and history of psychiatric problems. Depersonalisation was correlated with age, marital status, professional grade and history of psychiatric problems. Low levels of personal accomplishment increased with the number of patients under care, history of psychiatric problems and the regret of professional choice. CONCLUSION: Burn-out is a reality in oncology hospital with an alarming rate. Interventions including rationalisation of workload, support groups, training in emotion and stress management would improve the mental health of these nurses and increase their performance. The screening for burnout should be included as a regular practice in health promotion programmes for oncology health professionals, particularly for a vulnerable subgroup that possesses the risk mentioned above factors.

7.
J Med Case Rep ; 18(1): 233, 2024 May 02.
Artigo em Inglês | MEDLINE | ID: mdl-38693541

RESUMO

INTRODUCTION: Vaginal metastasis from colorectal cancer is a rare occurrence, typically associated with other metastatic lesions. Isolated metastasis is exceedingly uncommon, with only a few cases documented in the literature. Vaginal involvement in colorectal cancer primarily results from direct contiguous spread from the primary tumor. CASE PRESENTATION: We present the case of a 70-year-old African woman diagnosed with adenocarcinoma of the middle rectum. She underwent chemotherapy, radiotherapy, and subsequent anterior resection. After 2 months, an isolated metastasis of rectal cancer was identified in the lower third of the left vaginal wall, confirmed by biopsy. Colonoscopy ruled out colorectal recurrence. Thoraco-abdominal computed tomography scan showed no distant metastases. The patient underwent abdominoperineal resection, removing the lateral and posterior vaginal wall with free macroscopic margins and a definitive colostomy. The final histopathological analysis confirmed the diagnosis of moderately differentiated adenocarcinoma of the vagina, measuring 5 × 4.5 cm. The rectal wall was extrinsically invaded by the tumor down to the muscularis propria while respecting the rectal mucosa. Resection margins were negative. The patient was discharged 1 week postoperation with no complications. Adjuvant chemotherapy was indicated, and the patient is currently tolerating the treatment well. CONCLUSION: Vaginal metastases from colorectal cancer are extremely rare. A vigilant gynecological examination is recommended during the follow-up of colorectal cancer patients. Diagnosis can be challenging, especially if the metastatic lesion is small and asymptomatic, even after standard radiological examination. Surgical resection followed by chemotherapy is a valid option for patients with early isolated metastases.


Assuntos
Adenocarcinoma , Neoplasias Retais , Neoplasias Vaginais , Idoso , Feminino , Humanos , Adenocarcinoma/diagnóstico por imagem , Adenocarcinoma/patologia , Quimioterapia Adjuvante , Neoplasias Retais/patologia , Tomografia Computadorizada por Raios X , Resultado do Tratamento , Vagina/patologia , Neoplasias Vaginais/secundário , Neoplasias Vaginais/terapia
8.
J Investig Med High Impact Case Rep ; 12: 23247096241261309, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38884543

RESUMO

Rectal signet ring cell carcinoma represents a rare subtype of colorectal adenocarcinoma known for its aggressive biological nature and poor prognosis. Although the co-occurrence of colorectal carcinoma with other tumors has been reported, the uncommon phenomenon of tumor-to-tumor metastasis, first described in 1930, remains rare. The most frequent donor neoplasms are lung or breast carcinomas, whereas cerebral meningiomas have been reported to be the most frequent recipient neoplasms. Here we report a case of a typical lipomatous tumor harboring metastatic signet ring cell rectal carcinoma. It is about a 42-year-old man diagnosed with rectal signet ring cell carcinoma and treated with concurrent radiotherapy and chemotherapy followed by an anterior resection and manual coloanal anastomosis with a temporary ileostomy. During the surgery, an abdominal wall lipoma was discovered and excised. A histopathological examination revealed infiltration of the fibro adipose tissue by a mucinous adenocarcinoma with a contingent of signet ring cells. The patient died 12 months after adjuvant chemotherapy due to peritoneal progression. To the best of our understanding, this represents the initial documented instance of tumor-to-tumor metastasis from rectal signet cell carcinoma to a conventional nonvascular lipoma. Consequently, even if one of these tumors appears clinically and radiologically benign, it is prudent to entertain the prospect of tumor-to-tumor metastasis. Thus, a comprehensive pathologic study of both tumors is highly recommended.


Assuntos
Carcinoma de Células em Anel de Sinete , Lipoma , Neoplasias Retais , Humanos , Carcinoma de Células em Anel de Sinete/patologia , Carcinoma de Células em Anel de Sinete/secundário , Masculino , Neoplasias Retais/patologia , Adulto , Evolução Fatal , Lipoma/patologia , Adenocarcinoma Mucinoso/patologia , Adenocarcinoma Mucinoso/secundário
9.
ACS Omega ; 9(26): 28951-28960, 2024 Jul 02.
Artigo em Inglês | MEDLINE | ID: mdl-38973911

RESUMO

In the modern era of the Internet of Things, the potential role of flexible piezoelectric generators (PEG) reflects the rapid increase in self-powered devices and wearable technologies. In this study, a casting process to elaborate the polydimethylsiloxane (PDMS)/barium titanate (BaTiO 3) composite has been presented. The addition of 15 wt % BaTiO 3 microparticles into the PDMS polymer greatly enhances the piezoelectric coefficient (d 31 = 24 pC N-1), leading to an increased output voltage of approximately 4 V under finger tapping force. The proposed flexible microgenerator yielded an excellent piezoelectric figure of merit (FoM 31 = 13.1 × 10-12 m2 N-1), significantly enhancing successfully the energy-harvesting performance (power density of 35 nW/cm2). Furthermore, the fabricated lead-free PEG exhibited an excellent flexibility figure of merit (fFoM) due to the low young modulus values (Maximum E = 3.4 MPa). These results indicate efficient energy conversion and demonstrate a favorable balance between the flexibility and piezoelectric properties of the composite, highlighting its potential for a wide range of applications in self-powered wearable sensors able to collect different human motions in applications such as gesture tracking and finger motion detection.

10.
J Med Case Rep ; 18(1): 108, 2024 Feb 24.
Artigo em Inglês | MEDLINE | ID: mdl-38395921

RESUMO

INTRODUCTION: Primary Thyroid Lymphoma (PTL) is defined as lymphoma involving the thyroid gland alone or the thyroid gland and adjacent neck lymph nodes without contiguous spread or distant metastases at the time of diagnosis. Most thyroid lymphomas are B cell lymphomas, and 98% of all PTL cases are non-Hodgkin's lymphoma. It is a rare disease accounting for around 5% of the thyroid neoplasms and 2% of extranodal lymphomas. If properly diagnosed and treated, the prognosis is favorable. CASE PRESENTATION: Five cases (three men and two women) of PTL were diagnosed and treated in our institute between January 2005 and September 2019. These are 5 cases of Caucasian origin. The mean age was 76.2 (range: 63-95 years); one patient had associated hypothyroid. One patient had a medical history of breast cancer; one was hypothyroid, and four were euthyroid at the diagnosis. In 4 of these patients, PTL started with compressive symptoms. No patients underwent fine needle aspiration cytology (FNAC) or biopsy for the diagnostic only. In sonography, two cases showed bilateral nodules with goiter; in the three cases it showed nodules in the lobe and isthmus. Technetium-99m scintigraphy was performed on only two patients. Bone Marrow Biopsy (BMB) showed normal cellularity in 4 cases and only one case showed tumor cells. LDH levels were increased in all cases. The extension was evaluated in all patients with cervical and thoracic CT scans, Bone Marrow Biopsy (BMB), beta-2 microglobulin, and serum lactate dehydrogenase (LDH) levels. Three cases were staged as IE and two cases as IIE. Three patients underwent total thyroidectomy; two of them underwent cervical lymph node dissection. Two patients underwent lobectomy. All were diagnosed with lymphoma postoperatively and all were diffuse large B cell lymphoma (DLBCL). One patient completed treatment with R-CHOP (Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone), and two cases received adjuvant chemo-radiotherapy (30 Gy). Two patients died immediately after surgery. CONCLUSION: PTL is a rare disease whose diagnosis should be considered in cases of rapidly growing goitres. Timely needle biopsy in suspected cases can avoid unnecessary surgery. Systemic treatment is required, depending on the stage of the tumour.


Assuntos
Linfoma Difuso de Grandes Células B , Linfoma não Hodgkin , Neoplasias da Glândula Tireoide , Masculino , Humanos , Feminino , Idoso , Doenças Raras , Neoplasias da Glândula Tireoide/patologia , Doxorrubicina/uso terapêutico , Linfoma Difuso de Grandes Células B/diagnóstico , Linfoma Difuso de Grandes Células B/terapia , Linfoma Difuso de Grandes Células B/patologia , Prednisona/uso terapêutico , Vincristina/uso terapêutico , Rituximab , Ciclofosfamida/uso terapêutico , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico
11.
J Med Case Rep ; 18(1): 36, 2024 Jan 30.
Artigo em Inglês | MEDLINE | ID: mdl-38287377

RESUMO

BACKGROUND: Nasopharyngeal carcinoma is known for its high potential for regional and distant metastasis. However, breast metastasis is rarely reported. CASE PRESENTATION: A 39-year-old Caucasian male presented with bilateral neck lymph node enlargement. Radiological examination with contrast-enhanced computed tomography scan and breast imaging revealed an enhancing mass lesion in the right breast. Histopathology of the nasopharynx mass was suggestive of undifferentiated nasopharyngeal carcinoma. A breast biopsy confirmed the diagnosis of synchronous breast metastasis from the nasopharyngeal carcinoma. We present this study to illustrate that Nasopharyngeal carcinoma can metastasize to the male breast. Furthermore, the high incidence of nasopharyngeal carcinoma metastasis underscores the pressing need to identify effective and safe strategies, emphasizing the importance of utilizing computed tomography scans for metastasis detection. CONCLUSION: The present study illustrates the first case of synchronous male breast metastases from nasopharyngeal carcinoma. Thus, it is critical to distinguish between metastatic pathology and coexisting second malignancies to plan appropriate therapy.


Assuntos
Neoplasias da Mama Masculina , Carcinoma Nasofaríngeo , Neoplasias Nasofaríngeas , Segunda Neoplasia Primária , Adulto , Humanos , Masculino , Carcinoma Nasofaríngeo/patologia , Neoplasias Nasofaríngeas/patologia , Segunda Neoplasia Primária/patologia , Neoplasias da Mama Masculina/patologia
12.
J Sci Food Agric ; 93(3): 527-34, 2013 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-22886385

RESUMO

BACKGROUND: The aim of this work was to study the chemical characteristics of two Tunisian cultivars, namely Dhokar and Gemri-Dhokar, to analyse the fatty acids, sterols, triacylglycerols, triterpenic alcohols, and to determine the phenolic composition and oxidative stability. RESULTS: Among the rare varieties, Gemri-Dhokar olive oil had the highest value of oleic acid (69.39%) whereas Dhokar oil was noteworthy for its lower content of phenolic compounds (94.56 mg kg(-1) gallic acid equivalents of oil) and presented the highest level of palmitic acid (19.37%). The main sterols found in all olive oil samples were ß-sitosterol and Δ5-avenasterol, whereas cholesterol and 24-methylenecholesterol were also found in all samples but in lower amounts. Two triterpenic dialcohols (erythrodiol and uvaol) were also detected and their content ranged from 1.45 to 2.30%, in Gemri-Dhokar and Dhokar olive oil, respectively. Ten phenolic compounds were identified. In all samples, the main phenols found were oleuropein aglycon and pinoresinol. These phenolic compounds showed significant correlations with oxidative stability. CONCLUSION: The analytical parameters of two oils that were determined in this study were greatly influenced by genetic factors (cultivar).


Assuntos
Fenóis/análise , Óleos de Plantas/química , Álcoois/análise , Estabilidade de Medicamentos , Ácidos Graxos/análise , Furanos/análise , Glucosídeos Iridoides , Iridoides , Lignanas/análise , Ácido Oleanólico/análogos & derivados , Ácido Oleanólico/análise , Azeite de Oliva , Oxirredução , Ácido Palmítico/análise , Fitosteróis/análise , Óleos de Plantas/classificação , Piranos/análise , Sitosteroides/análise , Especificidade da Espécie , Triglicerídeos/análise , Triterpenos/análise , Tunísia
13.
J Med Case Rep ; 17(1): 315, 2023 Jul 23.
Artigo em Inglês | MEDLINE | ID: mdl-37481539

RESUMO

INTRODUCTION: Cutaneous metastases (CM) revealing lung carcinoma are extremely rare, accounting for 0.8%. The diagnosis is guided by histology and immunohistochemistry. Treatment is palliative. The prognosis is poor. CASE PRESENTATION: This is a retrospective study of the available clinical and histological records of four North African patients with CM revealing lung cancer treated at our institute between 2004 and 2010. Three men and one woman were registered. The mean age was 54.5 years (38-74 years). Two patients had primary adenocarcinoma, one patient had small cell carcinoma and one had squamous cell carcinoma. Treatment was based on chemotherapy in two cases and antalgic radiotherapy in two cases, one patient underwent surgical resection as the lesion was infected. The overall survival after diagnosis was between one and four months. CONCLUSIONS: A skin nodule can be the first symptom revealing lung cancer. A rare clinical presentation that should not be taken for a benign nodule, the biopsy and histological study with immunohistochemistry confirm the diagnosis.


Assuntos
Carcinoma de Células Pequenas , Neoplasias Pulmonares , Neoplasias Cutâneas , Carcinoma de Pequenas Células do Pulmão , Masculino , Feminino , Humanos , Pessoa de Meia-Idade , Estudos Retrospectivos , Pulmão
14.
Womens Health (Lond) ; 19: 17455057231181009, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37480326

RESUMO

Pelvic actinomycosis with an intrauterine device accounts for approximately 3% of all actinomycoses. It is a chronic infectious disease characterized by infiltrative, suppurative, or granulomatous inflammation, sinus fistula formation, and extensive fibrosis, and caused by filamentous, gram-positive, anaerobic bacteria called Actinomyces israelii. The slow and silent progression favors pseudo tumor pelvic extension and exposes the patient to acute life-threatening complications, namely colonic occlusion with hydronephrosis. Preoperative diagnosis is often difficult due to the absence of specific symptomatology and pathognomonic radiological signs simulating pelvic cancer. We discuss the case of a 67-year-old woman who complained of pelvic pain, constipation, and weight loss for 4 months, and who presented to the emergency department with a picture of colonic obstruction and a biological inflammatory syndrome. The computed tomography scan revealed a suspicious heterogeneous pelvic mass infiltrating the uterus with an intrauterine device, the sigmoid with extensive upstream colonic distension, and right hydronephrosis. The patient underwent emergency surgery with segmental colonic resection and temporary colostomy, followed by antibiotic therapy. The favorable clinical and radiological evolution under prolonged antibiotic therapy with the almost total disappearance of the pelvic pseudo tumor infiltration confirms the diagnosis of pelvic actinomycosis and thus makes it possible to avoid an extensive and mutilating surgery with important morbidity.


Assuntos
Actinomicose , Hidronefrose , Dispositivos Intrauterinos , Neoplasias , Feminino , Humanos , Idoso , Actinomicose/complicações , Actinomicose/diagnóstico , Actinomicose/cirurgia , Hidronefrose/diagnóstico por imagem , Hidronefrose/etiologia , Hidronefrose/cirurgia , Antibacterianos/uso terapêutico , Dor Pélvica/tratamento farmacológico , Dispositivos Intrauterinos/efeitos adversos
15.
Food Chem Toxicol ; 178: 113929, 2023 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-37406758

RESUMO

Cow's milk proteins allergy (CMA) is an atypical immune system response to cow's milk and dairy products. It's one of the most common food allergies in children affecting 8% of the total pediatric population pediatric population. This comprehensive review examines recent studies in CMA, especially regarding mammalian milk allergies such as goat's, sheep's, buffalo's, camel's, mare's and donkey's milk allergies in order to increase awareness of these selective allergies and to reduce allergy risks for those who have them. The consumption of other mammalian milk types is not recommended because of the significant homology between milk proteins from cow, sheep, goat and buffalo resulting in clinical cross-reactivity. However, camel's, mare's or donkey's milk may be tolerated by some allergic patients. Selective mammalian milk allergies are unusual and rare disorders characterized by severe symptoms including angio-oedema, urticaria, respiratory manifestations and anaphylaxis. Based on the reported allergic cases, cheese products including Ricotta, Romano, Pecorino and Mozzarella, are considered as the most common source of allergens especially in goat's, sheep's and buffalo's milk allergies, while the major allergens in donkey's and mare's milk seems to be whey proteins including lysozyme, α-lactalbumin and ß-lactogloblin due to the low casein/whey proteins ratio in equine's milk.


Assuntos
Hipersensibilidade a Leite , Proteínas do Leite , Cavalos , Criança , Animais , Humanos , Feminino , Bovinos , Ovinos , Proteínas do Soro do Leite , Búfalos , Camelus , Testes Cutâneos/efeitos adversos , Alérgenos , Cabras , Equidae
16.
Ann Med Surg (Lond) ; 85(5): 2046-2048, 2023 May.
Artigo em Inglês | MEDLINE | ID: mdl-37228962

RESUMO

Secondary psychiatric symptoms are usually suspected when there is an atypical presentation of the symptoms or a lack of response to psychotropic medication. Case presentation: Our case is about a woman aged 62 years old, with a history of mental disorder who presented psychiatric symptomatology after years of being stabilized by antipsychotics. She was later investigated due to a mass in her breast. Carcinoma was diagnosed, and her psychiatric symptomatology was resolved after the tumerectomy. Discussion: The therapeutic difficulty is the major problem of psychic disorders in the context of paraneoplastic syndrome. Several literature review have suggested a relationship between schizophrenia and antineuronal antibodies in the context of paraneoplastic syndrome. Treating the tumor can solve psychiatric symptoms better than psychotic treatment. Conclusions: The aim of our study is to highlight the importance of a complete medical evaluation to identify the psychiatric presentations of organic disorders associated with psychiatric manifestation and to ensure an early diagnosis.

17.
Front Nutr ; 10: 1295878, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-38274210

RESUMO

Introduction: This work presents proteins, amino acids profiles and antioxidant and properties of camel and cow milk fractions produced using an integrated coagulation-centrifugation process. Methods: Antioxidant activity using DPPH radical scavenging assay; and antidiabetic activity antidiabetic activity using in vitro α-amylase inhibitory activity were assessed on defatted milk fractions and their extracts using water/ethanol or HCl/ethanol solvents. Protein profiles and amino acids composition were analyzed by high-performance liquid chromatography. Results and discussions: The predominant protein found in cow and camel milk was ß-casein in sodium caseinate, ß-lactoglobulin was found in the whey of cow milk, whereas α-lactalbumin was detected in the whey fractions of camel. The primary amino acids (comprising 1% to 5.2%) in skim milk and sweet whey milk were leucine, proline, and lysine. However, acid whey, casein fractions (sodium caseinate, and ß-casein) from both camel and cow milk exhibited elevated concentrations of histidine, leucine, lysine and proline (1.12 - 6.62%). Camel milk and its different protein fractions showed an interesting in vitro α-amylase inhibitory activity varying, according to different milk fractions and extraction methods, from 19.10 ± 1.40 to 97.40 ± 1.50%. Whatever the used method, the whey fractions from camel milk, both acid and sweet, displayed ed the highest antioxidant activity. Principal components analysis showed a positive correlation between the total phenols content, antioxidant (DPPH assay) and antidiabetic (α amylase inhibition test) activities within the milk fractions. Sweet and acid cow milk fractions seem to be the most promising for deeper exploration of in vivo biological activities and are promising milk derivatives for specific nutritional diet and/or functional food formulation.

18.
Lipids Health Dis ; 11: 35, 2012 Mar 06.
Artigo em Inglês | MEDLINE | ID: mdl-22394592

RESUMO

BACKGROUND: Increasing consumer demand for healthier food products has led to the development of governmental policies regarding health claims in many developed countries. In this context, contamination of poultry by food-borne pathogens is considered one of the major problems facing the progress of the poultry industry in Tunisia. RESULT: Zeolite (Clinoptilolites) was added to chicken feed at concentrations 0,5% or 1% and was evaluated for its effectiveness to reduce total flora in chickens and its effects on performance of the production. The broilers were given free and continuous access to a nutritionally non-limiting diet (in meal form)that was either a basal diet or a' zeolite diet' (the basal diet supplemented with clinoptilolite at a level of 0,5% or 1%). It was found that adding zeolite in the broiler diet significantly (p < 0,05) reduced total flora levels, as compared to the control, on the chicken body. In addition, it was found that zeolite treatment had a positive effect on performance production and organoleptic parameters that were measured and mainly on the increase level of Omega 3 fatty acid. CONCLUSION: This study showed the significance of using zeolite, as a feed additive for broilers, as part of a comprehensive program to control total flora at the broiler farm and to increase level of Omega 3 fatty acid on the chicken body.


Assuntos
Ração Animal/análise , Galinhas/metabolismo , Galinhas/microbiologia , Ácidos Graxos Ômega-3/biossíntese , Aditivos Alimentares/farmacologia , Carne/análise , Zeolitas/farmacologia , Animais , Soluções Tampão , Suplementos Nutricionais , Intestinos/efeitos dos fármacos , Intestinos/microbiologia , Músculo Esquelético/efeitos dos fármacos , Músculo Esquelético/metabolismo , Peptonas/farmacologia , Aves Domésticas , Coxa da Perna , Tunísia , Água/química
19.
ScientificWorldJournal ; 2012: 535781, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-22654625

RESUMO

In the present work the use of treated wastewater (TWW) to irrigate olive plants was monitored. This type of water is characterized by high salinity and retains a substantial amount of trace elements, organic and metallic compounds that can be transferred into the soil and into the plants and fruits. In order to evaluate the impact of TWW on the overall quality of the oils, the time of contact of the olives with the soil has been taken into account. Multi-element data were obtained using ICP-MS. Nineteen elements (Li, B, Na, Mg, Al, K, Ca, Sc, Cr, Mn, Fe, Co, Ni, Cu, Zn, Sr, Mo, Ba and La) were submitted for statistical analysis. Using analysis of variance, linear discriminant analysis and principal component analysis it was possible to differentiate between oils produced from different batches of olives whose plants received different types of water. Also, the results showed that there was correlation between the elemental and mineral composition of the water used to irrigate the olive plots and the elemental and mineral composition of the oils.


Assuntos
Irrigação Agrícola , Óleos de Plantas/química , Oligoelementos/análise , Poluentes Químicos da Água/toxicidade , Olea/efeitos dos fármacos , Azeite de Oliva , Análise de Componente Principal , Tunísia
20.
Tunis Med ; 90(10): 692-7, 2012 Oct.
Artigo em Francês | MEDLINE | ID: mdl-23096508

RESUMO

BACKGROUND: Disseminated intravascular coagulation (DIC) in obstetric disorders is a severe complication. AIM: To study the frequency and means of diagnosis of DIC and the therapeutic care and maternal morbidity induced. METHODS: Monocentric, prospective and descriptive study about 45 cases of intravascular coagulation in an obstetrical service collected at the University Hospital of Obstetrics and Gynecology Hedi Chaker of Sfax over a period ranging from June 2007 to June 2010. All the pregnant patients who have given birth beyond 28 weeks and have presented a DIC were selected for this study. RESULTS: The mean age of patients was 31.4 years. The mean parity was 2.6. The main diseases during pregnancy were: severe preeclampsia (22.2%), diabetes (28.8%), intrauterine fetal death (17.7%), previa placenta (8.8%). The main causes of DIC were: uterine atony (44.4%), abruptio placenta (22.2%), Hellp syndrome (11.1%) and uterine rupture (6, 6%). The lowest rate of platelets was 21000/mm3. The fibrinogen level was <0.5 g in 40% of cases. Despite reanimation and transfusion with blood products, surgical treatment was necessary in 77.7% of cases. All the patients were transferred in intensive care unit with an average stay of about three days. No maternal death was reported. CONCLUSION: DIC is a frequent complication of many obstetrical diseases. The treatment is urgent. It requires first to the cause and the shock by massive transfusions of packed red blood cells, fresh frozen plasma, and platelets, associated with antifibrinolytic drugs, if necessary.


Assuntos
Coagulação Intravascular Disseminada/etiologia , Coagulação Intravascular Disseminada/terapia , Complicações Hematológicas na Gravidez/etiologia , Complicações Hematológicas na Gravidez/terapia , Adulto , Transfusão de Sangue/estatística & dados numéricos , Feminino , Humanos , Gravidez , Estudos Prospectivos , Adulto Jovem
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