Detalhe da pesquisa
1.
Nonselective TRPC channel inhibition and suppression of aminoglycoside-induced premature termination codon readthrough by the small molecule AC1903.
J Biol Chem
; 298(2): 101546, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34999117
2.
Effect of small molecule eRF3 degraders on premature termination codon readthrough.
Nucleic Acids Res
; 49(7): 3692-3708, 2021 04 19.
Artigo
Inglês
| MEDLINE | ID: mdl-33764477
3.
Gentamicin B1 is a minor gentamicin component with major nonsense mutation suppression activity.
Proc Natl Acad Sci U S A
; 114(13): 3479-3484, 2017 03 28.
Artigo
Inglês
| MEDLINE | ID: mdl-28289221
4.
Virtual Screening Identifies Chebulagic Acid as an Inhibitor of the M2(S31N) Viral Ion Channel and Influenza A Virus.
Molecules
; 25(12)2020 Jun 24.
Artigo
Inglês
| MEDLINE | ID: mdl-32599753
5.
Novel small molecules potentiate premature termination codon readthrough by aminoglycosides.
Nucleic Acids Res
; 44(14): 6583-98, 2016 08 19.
Artigo
Inglês
| MEDLINE | ID: mdl-27407112
6.
Nitazoxanide stimulates autophagy and inhibits mTORC1 signaling and intracellular proliferation of Mycobacterium tuberculosis.
PLoS Pathog
; 8(5): e1002691, 2012.
Artigo
Inglês
| MEDLINE | ID: mdl-22589723
7.
Structure-activity analysis of niclosamide reveals potential role for cytoplasmic pH in control of mammalian target of rapamycin complex 1 (mTORC1) signaling.
J Biol Chem
; 287(21): 17530-17545, 2012 May 18.
Artigo
Inglês
| MEDLINE | ID: mdl-22474287
8.
Hortonones A to C, hydroazulenones from the genus Hortonia.
J Nat Prod
; 75(6): 1189-91, 2012 Jun 22.
Artigo
Inglês
| MEDLINE | ID: mdl-22626446
9.
Clionamines stimulate autophagy, inhibit Mycobacterium tuberculosis survival in macrophages, and target Pik1.
Cell Chem Biol
; 29(5): 870-882.e11, 2022 05 19.
Artigo
Inglês
| MEDLINE | ID: mdl-34520745
10.
A Multipronged Screening Approach Targeting Inhibition of ETV6 PNT Domain Polymerization.
SLAS Discov
; 26(5): 698-711, 2021 06.
Artigo
Inglês
| MEDLINE | ID: mdl-33345679
11.
Bafilomycins produced in culture by Streptomyces spp. isolated from marine habitats are potent inhibitors of autophagy.
J Nat Prod
; 73(3): 422-7, 2010 Mar 26.
Artigo
Inglês
| MEDLINE | ID: mdl-20028134
12.
Raloxifene prevents stress granule dissolution, impairs translational control and promotes cell death during hypoxia in glioblastoma cells.
Cell Death Dis
; 11(11): 989, 2020 11 17.
Artigo
Inglês
| MEDLINE | ID: mdl-33203845
13.
Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency.
Mol Neurodegener
; 15(1): 21, 2020 03 16.
Artigo
Inglês
| MEDLINE | ID: mdl-32178712
14.
Screening for chemical inhibitors of heterologous proteins expressed in yeast using a simple growth-restoration assay.
Methods Mol Biol
; 486: 125-37, 2009.
Artigo
Inglês
| MEDLINE | ID: mdl-19347620
15.
2-Aminothiazole-4-carboxamides Enhance Readthrough of Premature Termination Codons by Aminoglycosides.
ACS Med Chem Lett
; 10(5): 726-731, 2019 May 09.
Artigo
Inglês
| MEDLINE | ID: mdl-31097990
16.
Novel spirothiazamenthane inhibitors of the influenza A M2 proton channel.
Eur J Med Chem
; 120: 64-73, 2016 Sep 14.
Artigo
Inglês
| MEDLINE | ID: mdl-27187859
17.
Induction of Covalently Crosslinked p62 Oligomers with Reduced Binding to Polyubiquitinated Proteins by the Autophagy Inhibitor Verteporfin.
PLoS One
; 9(12): e114964, 2014.
Artigo
Inglês
| MEDLINE | ID: mdl-25494214
18.
Inhibitors of the influenza A virus M2 proton channel discovered using a high-throughput yeast growth restoration assay.
PLoS One
; 8(2): e55271, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23383318
19.
Regulation of mTORC1 signaling by pH.
PLoS One
; 6(6): e21549, 2011.
Artigo
Inglês
| MEDLINE | ID: mdl-21738705
20.
Niclosamide prevents the formation of large ubiquitin-containing aggregates caused by proteasome inhibition.
PLoS One
; 5(12): e14410, 2010 Dec 23.
Artigo
Inglês
| MEDLINE | ID: mdl-21203451