Detalhe da pesquisa
1.
Repeated-Dose Toxicity, Biodistribution, and Shedding Assessments With a ChAd155 Respiratory Syncytial Virus Vaccine Candidate Evaluated in Rabbits and Rats.
Int J Toxicol
; 41(4): 263-275, 2022 08.
Artigo
Inglês
| MEDLINE | ID: mdl-35653115
2.
Repeated Dose Toxicity Study and Developmental and Reproductive Toxicology Studies of a Respiratory Syncytial Virus Candidate Vaccine in Rabbits and Rats.
Int J Toxicol
; 40(2): 125-142, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-33517807
3.
Chimeric hemagglutinin supra-seasonal universal influenza vaccine candidates administered sequentially by the intramuscular route are locally and systemically well-tolerated in rabbits.
Regul Toxicol Pharmacol
; 113: 104625, 2020 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-32119974
4.
Antithrombotic drug candidate ALX-0081 shows superior preclinical efficacy and safety compared with currently marketed antiplatelet drugs.
Blood
; 118(3): 757-65, 2011 Jul 21.
Artigo
Inglês
| MEDLINE | ID: mdl-21576702
5.
Benzoxazole and benzothiazole amides as novel pharmacokinetic enhancers of HIV protease inhibitors.
Bioorg Med Chem Lett
; 22(15): 4998-5002, 2012 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-22765892
6.
New helicase-primase inhibitors as drug candidates for the treatment of herpes simplex disease.
Nat Med
; 8(4): 392-8, 2002 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-11927946
7.
In vitro and in vivo activities of the novel anticytomegalovirus compound AIC246.
Antimicrob Agents Chemother
; 54(3): 1290-7, 2010 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-20047911
8.
Superior efficacy of helicase-primase inhibitor BAY 57-1293 for herpes infection and latency in the guinea pig model of human genital herpes disease.
Antivir Chem Chemother
; 18(1): 35-48, 2007.
Artigo
Inglês
| MEDLINE | ID: mdl-17354650
9.
The preclinical pharmacology of the high affinity anti-IL-6R Nanobody® ALX-0061 supports its clinical development in rheumatoid arthritis.
Arthritis Res Ther
; 17: 135, 2015 May 20.
Artigo
Inglês
| MEDLINE | ID: mdl-25994180